(Q38603140)

English

A novel approach in the treatment of neuroendocrine gastrointestinal tumours. Targeting the epidermal growth factor receptor by gefitinib (ZD1839)

scientific article published on November 3, 2003

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scholarly article

1 reference

Europe PubMed Central

4 September 2017

A novel approach in the treatment of neuroendocrine gastrointestinal tumours. Targeting the epidermal growth factor receptor by gefitinib (ZD1839) (English)

1 reference

10.1038/SJ.BJC.6601346

https://api.crossref.org/works/10.1038/SJ.BJC.6601346

26 March 2024

1 reference

10.1038/SJ.BJC.6601346

https://api.crossref.org/works/10.1038/SJ.BJC.6601346

26 March 2024

author name string

M. Höpfner

1

1 reference

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26 March 2024

A. P. Sutter

2

1 reference

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26 March 2024

B. Gerst

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14583782

26 March 2024

M. Zeitz

4

1 reference

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26 March 2024

H. Scherübl

5

1 reference

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26 March 2024

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publication date

1 November 2003

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Europe PubMed Central

4 September 2017

3 November 2003

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National Center for Biotechnology Information

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26 March 2024

full work available at URL

https://www.nature.com/articles/6601346.pdf

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Europe PubMed Central

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26 March 2024

https://europepmc.org/articles/PMC2394425

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14583782

26 March 2024

https://europepmc.org/articles/PMC2394425?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14583782

26 March 2024

http://www.nature.com/articles/6601346.pdf

Portable Document Format

1 reference

10.1038/SJ.BJC.6601346

https://api.crossref.org/works/10.1038/SJ.BJC.6601346

26 March 2024

http://www.nature.com/articles/6601346

1 reference

10.1038/SJ.BJC.6601346

https://api.crossref.org/works/10.1038/SJ.BJC.6601346

26 March 2024

British Journal of Cancer

1 reference

Europe PubMed Central

4 September 2017

89

1 reference

Europe PubMed Central

4 September 2017

1766-1775

1 reference

Europe PubMed Central

4 September 2017

9

1 reference

Europe PubMed Central

4 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.bjc.6601346

0 references

Antibody-mediated EGF receptor blockade as an anticancer therapy: from the laboratory to the clinic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

The epidermal growth factor receptor-tyrosine kinase: a promising therapeutic target in solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

Targeting the epidermal growth factor receptor for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

Epidermal growth factor receptor dependence in human tumors: more than just expression?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

Why the epidermal growth factor receptor? The rationale for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

ZD1839: targeting the epidermal growth factor receptor in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

Targeting the EGF receptor in ovarian cancer with the tyrosine kinase inhibitor ZD 1839 ("Iressa").

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

Extracellular nucleotides inhibit growth of human oesophageal cancer cells via P2Y(2)-receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

Chemotherapy and biotherapy in the treatment of neuroendocrine tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human colorectal cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

The role of hormones, growth factors and their receptors in pituitary tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

Peroxynitrite induces GADD34, 45, and 153 VIA p38 MAPK in human neuroblastoma SH-SY5Y cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

The epidermal growth factor receptor and its inhibition in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

Multiple positive and negative regulators of signaling by the EGF-receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

Mitochondrial control of nuclear apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

6 September 2017

Palliative effect of metaiodobenzylguanidine in metastatic carcinoid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

14 September 2017

Expression of growth factors and their receptors in neuroendocrine gut and pancreatic tumors, and prognostic factors for survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

14 September 2017

Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

27 September 2017

Meta-iodobenzylguanidine induces growth inhibition and apoptosis of neuroendocrine gastrointestinal tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

27 September 2017

Expression of dopamine receptors and transporter in neuroendocrine gastrointestinal tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

27 September 2017

Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

27 September 2017

Beta-cell gene expression and functional characterisation of the human insulinoma cell line CM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

27 September 2017

Expression of functional GABAA receptors in cholecystokinin-secreting gut neuroendocrine murine STC-1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

27 September 2017

Hyperosmolality causes growth arrest of murine kidney cells. Induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

27 September 2017

Growth factors and carcinoid tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

27 September 2017

Drug therapy in metastatic neuroendocrine tumors of the gastroenteropancreatic system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

27 September 2017

Growth inhibition and apoptosis induced by P2Y2 receptors in human colorectal carcinoma cells: involvement of intracellular calcium and cyclic adenosine monophosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

23 June 2018

gamma-Aminobutyric acid secretion from pancreatic neuroendocrine cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

23 June 2018

Increased epidermal growth factor receptor in multidrug-resistant human neuroblastoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

23 June 2018

Hypericin activated by an incoherent light source has photodynamic effects on esophageal cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

31 August 2018

Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human esophageal cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

31 August 2018

Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

31 August 2018

Cooperative inhibitory effect of ZD1839 (Iressa) in combination with trastuzumab (Herceptin) on human breast cancer cell growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

31 August 2018

Activated extracellular signal-regulated kinases: association with epidermal growth factor receptor/transforming growth factor alpha expression in head and neck squamous carcinoma and inhibition by anti-epidermal growth factor receptor treatments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

31 August 2018

Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer Is correlated with survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

31 August 2018

Blockade of growth factor receptors in ductal carcinoma in situ inhibits epithelial proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

31 August 2018

mRNA expression patterns of insulin-like growth factor system components in human neuroendocrine tumours.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

31 August 2018

Growth factor receptor expression in human gastroenteropancreatic neuroendocrine tumours.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

31 August 2018

Altered gene expression in drug-resistant human breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

31 August 2018

Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

31 August 2018

Chemoprevention of breast cancer: a model for change

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6601346

21 January 2018

Expression of epidermal growth factor receptor correlates with disease relapse and progression to androgen-independence in human prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

4 November 2018

Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2394425

4 November 2018

Expression of c-Myc, TGF-alpha and EGF-receptor in sporadic medullary thyroid carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14583782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of transforming growth factor alpha and its receptor in human neuroendocrine tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/14583782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14583782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of caspase-4(-like) protease in Fas-mediated apoptotic pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/14583782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor blockade by antibody IMC-C225 inhibits growth of a human pancreatic carcinoma xenograft in nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14583782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth characteristics of rectal carcinoid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14583782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14583782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of epidermal growth factor and hepatocyte growth factor receptors in a proportion of gastrinomas correlates with aggressive growth and lower curability

1 reference

https://pubmed.ncbi.nlm.nih.gov/14583782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proceedings of the American Association for Cancer Research

11

41

537

author name string

C Cullinane

publication date

2000

1 reference

10.1038/SJ.BJC.6601346

https://api.crossref.org/works/10.1038/SJ.BJC.6601346

26 March 2024

Proceedings of the American Association for Cancer Research

22

43

A3901

author name string

ML Janmaat

publication date

2002

1 reference

10.1038/SJ.BJC.6601346

https://api.crossref.org/works/10.1038/SJ.BJC.6601346

26 March 2024

Proceedings of the American Association for Cancer Research

31

42

805

author name string

A Meye

publication date

2001

1 reference

10.1038/SJ.BJC.6601346

https://api.crossref.org/works/10.1038/SJ.BJC.6601346

26 March 2024

Identifiers

10.1038/SJ.BJC.6601346

1 reference

Europe PubMed Central

4 September 2017

Dimensions Publication ID

0 references

release_4olltqzqwvgcxbultyxct2ebwu

1 reference

https://api.fatcat.wiki/v0/release/4olltqzqwvgcxbultyxct2ebwu

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

4 September 2017

1 reference

Europe PubMed Central

4 September 2017

ResearchGate publication ID

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