(Q38668336)

5 September 2017

title

NFKB1: a suppressor of inflammation, ageing and cancer (English)

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5 September 2017

Tyrell Cartwright

1

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author name string

Neil D Perkins

series ordinal

2

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5 September 2017

Caroline L Wilson

series ordinal

3

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5 September 2017

language of work or name

English

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publication date

14 December 2015

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5 September 2017

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5 September 2017

volume

283

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5 September 2017

issue

10

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5 September 2017

page(s)

1812-1822

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5 September 2017

cites work

The NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13627

IkappaBNS inhibits induction of a subset of Toll-like receptor-dependent genes and limits inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

A new member of the I kappaB protein family, I kappaB epsilon, inhibits RelA (p65)-mediated NF-kappaB transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

The nuclear I kappaB protein I kappaB zeta specifically binds NF-kappaB p50 homodimers and forms a ternary complex on kappaB DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13627

I kappa B gamma, a 70 kd protein identical to the C-terminal half of p110 NF-kappa B: a new member of the I kappa B family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Regulation of NFKB1 proteins by the candidate oncoprotein BCL-3: generation of NF-kappa B homodimers from the cytoplasmic pool of p50-p105 and nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Integrating cell-signalling pathways with NF-kappaB and IKK function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Crosstalk in NF-κB signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Stability of the Rel homology domain is critical for generation of NF-kappa B p50 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

The 20S proteasome processes NF-kappaB1 p105 into p50 in a translation-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

NF-kappaB1 (p50) homodimers differentially regulate pro- and anti-inflammatory cytokines in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Phosphorylation of serine 337 of NF-kappaB p50 is critical for DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Characterization of the dimer interface of transcription factor NFkappaB p50 homodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

IκBβ enhances the generation of the low-affinity NFκB/RelA homodimer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Recognition and signaling by toll-like receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

NF-κB and the link between inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

The NF-kappaB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Negative regulation of toll-like receptor signaling by NF-kappaB p50 ubiquitination blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

BCL-3 and NF-kappaB p50 attenuate lipopolysaccharide-induced inflammatory responses in macrophages

21 January 2018

1 reference

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The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13627

EHMT1 protein binds to nuclear factor-κB p50 and represses gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

C/EBPα and C/EBPα oncoproteins regulate nfkb1 and displace histone deacetylases from NF-κB p50 homodimers to induce NF-κB target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Phosphorylation of NF-kappaB1/p105 by oncoprotein kinase Tpl2: implications for a novel mechanism of Tpl2 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

NF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Coordinate regulation of TPL-2 and NF-κB signaling in macrophages by NF-κB1 p105.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Casper/c-FLIP is physically and functionally associated with NF-kappaB1 p105.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

The specificity of innate immune responses is enforced by repression of interferon response elements by NF-κB p50

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

NF-kappa B p50 regulates C/EBP alpha expression and inflammatory cytokine-induced neutrophil production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Persistence and function of central and effector memory CD4+ T cells following infection with a gastrointestinal helminth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

NF-kappaB1 contributes to T cell-mediated control of Toxoplasma gondii in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

NF-kappa B1 p105 regulates T cell homeostasis and prevents chronic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Chronic inflammation and susceptibility to bacterial infections in mice lacking the polypeptide (p)105 precursor (NF-kappaB1) but expressing p50.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Nuclear factor-kappaB1 (p50) limits the inflammatory and fibrogenic responses to chronic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Resolution of renal inflammation: a new role for NF-kappaB1 (p50) in inflammatory kidney diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Nuclear factor-kappaB p50 limits inflammation and prevents lung injury during Escherichia coli pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Complex regulation of acute and chronic neuroinflammatory responses in mouse models deficient for nuclear factor kappa B p50 subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Inhibition of transcription by B cell Leukemia 3 (Bcl-3) protein requires interaction with nuclear factor κB (NF-κB) p50.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

NF-kappaB p50 facilitates neutrophil accumulation during LPS-induced pulmonary inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Loss of Nfkb1 leads to early onset aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

p50 (NF-κB1) is an effector protein in the cytotoxic response to DNA methylation damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

S-phase-dependent p50/NF-кB1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-κB p50 and a single nucleotide in the κB-site

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Proteolysis of NF-kappaB1 p105 is essential for T cell antigen receptor-induced proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Inhibition of NF-kappaB DNA binding by nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Enhancement of nuclear factor-kappa B acetylation by coactivator p300 and HIV-1 Tat proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Glycogen synthase kinase-3 beta regulates NF-kappa B1/p105 stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Direct phosphorylation of NF-kappaB1 p105 by the IkappaB kinase complex on serine 927 is essential for signal-induced p105 proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Identification of a ZU5 and death domain-containing inhibitor of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

Distinct roles for the NF- B1 and c-Rel transcription factors in the differentiation and survival of plasmacytoid and conventional dendritic cells activated by TLR-9 signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13627

21 January 2018

Identifiers

DOI

10.1111/FEBS.13627

1 reference

5 September 2017

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