(Q38736299)

6 September 2017

title

Natural products-prompted chemical biology: phenotypic screening and a new platform for target identification (English)

1 reference

natural product chemistry

6 September 2017

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26883503%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Hideaki Kakeya

series ordinal

1

1 reference

6 September 2017

publication date

17 February 2016

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6 September 2017

published in

Natural Product Reports

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26883503%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26883503%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26883503%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

648-654

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26883503%20AND%20SRC:MED&resulttype=core&format=json

Natural products as sources of new drugs over the 30 years from 1981 to 2010

13 June 2020

cites work

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How were new medicines discovered?

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Structure-activity relationships of epolactaene derivatives: structural requirements for inhibition of Hsp60 chaperone activity.

21 January 2018

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Epolactaene binds human Hsp60 Cys442 resulting in the inhibition of chaperone activity

21 January 2018

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Chaperone machines for protein folding, unfolding and disaggregation

21 January 2018

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Targeting mitochondrial transcription in fission yeast with ETB, an inhibitor of HSP60, the chaperone that binds to the mitochondrial transcription factor Mtf1.

21 January 2018

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Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology

21 January 2018

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The hypoxic tumor microenvironment: A driving force for breast cancer progression

21 January 2018

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Aberrant IDH3α expression promotes malignant tumor growth by inducing HIF-1-mediated metabolic reprogramming and angiogenesis.

21 January 2018

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UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α.

21 January 2018

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Design, synthesis, and structure-activity relationships of 1-ethylpyrazole-3-carboxamide compounds as novel hypoxia-inducible factor (HIF)-1 inhibitors.

21 January 2018

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Prediction and determination of the stereochemistry of the 1,3,5-trimethyl-substituted alkyl chain in verucopeptin, a microbial metabolite.

21 January 2018

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Structure Elucidation of Verucopeptin, a HIF-1 Inhibitory Polyketide-Hexapeptide Hybrid Metabolite from an Actinomycete.

21 January 2018

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Kettapeptin: isolation, structure elucidation and activity of a new hexadepsipeptide antibiotic from a terrestrial Streptomyces sp.

21 January 2018

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IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells.

21 January 2018

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Dentigerumycin: a bacterial mediator of an ant-fungus symbiosis

21 January 2018

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Retracted: Rapamycin Inhibits Proliferation of Hemangioma Endothelial Cells by Reducing HIF-1-Dependent Expression of VEGF

21 January 2018

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Creating diverse target-binding surfaces on FKBP12: synthesis and evaluation of a rapamycin analogue library

21 January 2018

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Cell membranes: the lipid perspective

21 January 2018

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Polarized growth in fungi--interplay between the cytoskeleton, positional markers and membrane domains.

21 January 2018

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Marine antifungal theonellamides target 3beta-hydroxysterol to activate Rho1 signaling

21 January 2018

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Aberrant development of functional connectivity among resting state-related functional networks in medication-naïve ADHD children

21 January 2018

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Bioactive Structure of Membrane Lipids and Natural Products Elucidated by a Chemistry-Based Approach.

21 January 2018

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Multiple functions of ergosterol in the fission yeast Schizosaccharomyces pombe.

21 January 2018

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Structure and biological activity of 8-deoxyheronamide C from a marine-derived Streptomyces sp.: heronamides target saturated hydrocarbon chains in lipid membranes.

21 January 2018

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Heronamides A-C, new polyketide macrolactams from an Australian marine-derived Streptomyces sp. A biosynthetic case for synchronized tandem electrocyclization.

21 January 2018

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5-Alkyl-1,2,3,4-tetrahydroquinolines, new membrane-interacting lipophilic metabolites produced by combined culture of Streptomyces nigrescens and Tsukamurella pulmonis.

21 January 2018

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Mycolic acid-containing bacteria induce natural-product biosynthesis in Streptomyces species

21 January 2018

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How chemoproteomics can enable drug discovery and development

21 January 2018

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Ligand-directed tosyl chemistry for protein labeling in vivo

21 January 2018

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LDAI-based chemical labeling of intact membrane proteins and its pulse-chase analysis under live cell conditions

21 January 2018

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Chemical tagging of a drug target using 5-sulfonyl tetrazole.

21 January 2018

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Emerging roles for lipids in shaping membrane-protein function.

21 January 2018

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Functional rafts in cell membranes

21 January 2018

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Uncovering the intimate relationship between lipids, cholesterol and GPCR activation

21 January 2018

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Photocrosslinking and click chemistry enable the specific detection of proteins interacting with phospholipids at the membrane interface

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5NP00120J

Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5NP00120J

In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5NP00120J

In Vivo Linking of Membrane Lipids and the Anion Transporter Band 3 with Thiourea-modified Amphiphilic Lipid Probes

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5NP00120J

Identification of HSP60 as a Primary Target ofo-Carboranylphenoxyacetanilide, an HIF-1α Inhibitor

21 January 2018

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Verucopeptin, a new antitumor antibiotic active against B16 melanoma. II. Structure determination

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.46.928

Identifiers

DOI

10.1039/C5NP00120J

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26883503%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference