(Q38900355)

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Porcine reproductive and respiratory syndrome virus nonstructural protein 2 (nsp2) topology and selective isoform integration in artificial membranes

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Europe PubMed Central

PubMed publication ID

7 September 2017

Porcine reproductive and respiratory syndrome virus nonstructural protein 2 (nsp2) topology and selective isoform integration in artificial membranes (English)

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Europe PubMed Central

PubMed publication ID

7 September 2017

porcine reproductive and respiratory syndrome

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porcine reproductive and respiratory syndrome virus

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Porcine reproductive and respiratory syndrome virus

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Cathy L. Miller

2

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Europe PubMed Central

PubMed publication ID

7 September 2017

author name string

Matthew A Kappes

1

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Europe PubMed Central

PubMed publication ID

7 September 2017

Kay S Faaberg

3

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Europe PubMed Central

PubMed publication ID

7 September 2017

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publication date

11 March 2015

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Europe PubMed Central

PubMed publication ID

7 September 2017

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Europe PubMed Central

PubMed publication ID

7 September 2017

481

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Europe PubMed Central

PubMed publication ID

7 September 2017

51-62

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Tail-anchored and signal-anchored proteins utilize overlapping pathways during membrane insertion

1 reference

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Signal recognition particle mediates post-translational targeting in eukaryotes

1 reference

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Post-translational integration of tail-anchored proteins is facilitated by defined molecular chaperones

1 reference

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Prediction of membrane-protein topology from first principles

1 reference

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TOPCONS: consensus prediction of membrane protein topology

1 reference

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Unassisted translocation of large polypeptide domains across phospholipid bilayers

1 reference

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Transmembrane topogenesis of a tail-anchored protein is modulated by membrane lipid composition

1 reference

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Sequential interplay between BAG6 and HSP70 upon heat shock

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The vOTU domain of highly-pathogenic porcine reproductive and respiratory syndrome virus displays a differential substrate preference

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The endosomal pathway and the Golgi complex are involved in the infectious bursal disease virus life cycle

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The envelope proteins of lactate dehydrogenase-elevating virus and their membrane topography

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A fast and inexpensive procedure for drying polyacrylamide gels

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Porcine reproductive and respiratory syndrome virus nonstructural protein 2 contributes to NF-κB activation

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The PRRSV replicase: exploring the multifunctionality of an intriguing set of nonstructural proteins

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Efficient -2 frameshifting by mammalian ribosomes to synthesize an additional arterivirus protein

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Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

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Two membrane-associated regions within the Nodamura virus RNA-dependent RNA polymerase are critical for both mitochondrial localization and RNA replication

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The endoplasmic reticulum provides the membrane platform for biogenesis of the flavivirus replication complex

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The porcine reproductive and respiratory syndrome virus nsp2 cysteine protease domain possesses both trans- and cis-cleavage activities

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Proteolytic Products of the Porcine Reproductive and Respiratory Syndrome Virus nsp2 Replicase Protein

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Protein targeting and degradation are coupled for elimination of mislocalized proteins

1 reference

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Viral reorganization of the secretory pathway generates distinct organelles for RNA replication

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A combined transmembrane topology and signal peptide prediction method

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Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway

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Highly divergent strains of porcine reproductive and respiratory syndrome virus incorporate multiple isoforms of nonstructural protein 2 into virions

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Ultrastructural characterization of arterivirus replication structures: reshaping the endoplasmic reticulum to accommodate viral RNA synthesis

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Chaperone action in the posttranslational topological reorientation of the hepatitis B virus large envelope protein: Implications for translocational regulation

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Bag6/Bat3/Scythe: a novel chaperone activity with diverse regulatory functions in protein biogenesis and degradation.

1 reference

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Bat3 promotes the membrane integration of tail-anchored proteins

1 reference

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The association of BAG6 with SGTA and tail-anchored proteins

1 reference

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Identification of porcine reproductive and respiratory syndrome virus ORF1a-encoded non-structural proteins in virus-infected cells

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Transactivation of programmed ribosomal frameshifting by a viral protein

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Reorientation of aquaporin-1 topology during maturation in the endoplasmic reticulum

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Rubella virus replication complexes are virus-modified lysosomes

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A ribosome-associating factor chaperones tail-anchored membrane proteins

1 reference

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Flock house virus RNA replicates on outer mitochondrial membranes in Drosophila cells.

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Structure, function and evolution of the signal recognition particle

1 reference

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Forced transmembrane orientation of hydrophilic polypeptide segments in multispanning membrane proteins

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Signal sequences influence membrane integration of the prion protein

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Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes

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Identification and evolution of dual-topology membrane proteins

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Bat3 deficiency accelerates the degradation of Hsp70-2/HspA2 during spermatogenesis

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Control of membrane protein topology by a single C-terminal residue

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MemBrain: improving the accuracy of predicting transmembrane helices

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Arterivirus molecular biology and pathogenesis

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Non-structural proteins 2 and 3 interact to modify host cell membranes during the formation of the arterivirus replication complex

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Nonstructural protein 2 of porcine reproductive and respiratory syndrome virus inhibits the antiviral function of interferon-stimulated gene 15.

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The HMMTOP transmembrane topology prediction server

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Membrane topology and insertion of membrane proteins: search for topogenic signals

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Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells

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Arterivirus and nairovirus ovarian tumor domain-containing Deubiquitinases target activated RIG-I to control innate immune signaling

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Best alpha-helical transmembrane protein topology predictions are achieved using hidden Markov models and evolutionary information

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OCTOPUS: improving topology prediction by two-track ANN-based preference scores and an extended topological grammar

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Signal sequences. The limits of variation

1 reference

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Membrane-protein topology

1 reference

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Membrane proteins: from bench to bits

1 reference

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Topogenic signals in integral membrane proteins

1 reference

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Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane

1 reference

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Interactome profile of the host cellular proteins and the nonstructural protein 2 of porcine reproductive and respiratory syndrome virus

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A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation

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Sequential recruitment of the endoplasmic reticulum and chloroplasts for plant potyvirus replication

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How translocons select transmembrane helices

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Virus-encoded proteinases and proteolytic processing in the Nidovirales.

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Open reading frame 1a-encoded subunits of the arterivirus replicase induce endoplasmic reticulum-derived double-membrane vesicles which carry the viral replication complex

1 reference

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10.1016/J.VIROL.2015.01.028

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

ResearchGate publication ID

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