(Q38981486)

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The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition.

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21 March 2020

The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition (English)

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21 March 2020

colorectal carcinoma

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Marco A. Pierotti

24

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21 March 2020

Andrea Sartore-Bianchi

22

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21 March 2020

Salvatore Siena

25

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21 March 2020

Silvio Marco Veronese

26

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21 March 2020

Marcello Gambacorta

23

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Marcello Gambacorta

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21 March 2020

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Elena Ardini

1

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21 March 2020

Roberta Bosotti

2

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21 March 2020

Andrea Lombardi Borgia

3

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21 March 2020

Cristina De Ponti

4

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21 March 2020

Alessio Somaschini

5

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21 March 2020

Rosaria Cammarota

6

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21 March 2020

Nadia Amboldi

7

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21 March 2020

Laura Raddrizzani

8

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21 March 2020

Andrea Milani

9

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21 March 2020

Paola Magnaghi

10

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21 March 2020

Dario Ballinari

11

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21 March 2020

Daniele Casero

12

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21 March 2020

Fabio Gasparri

13

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21 March 2020

Patrizia Banfi

14

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21 March 2020

Nilla Avanzi

15

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21 March 2020

Maria B Saccardo

16

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21 March 2020

Rachele Alzani

17

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21 March 2020

Tiziano Bandiera

18

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21 March 2020

Eduard Felder

19

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21 March 2020

Daniele Donati

20

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21 March 2020

Enrico Pesenti

21

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21 March 2020

Arturo Galvani

27

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21 March 2020

Antonella Isacchi

28

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21 March 2020

publication date

12 June 2014

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21 March 2020

Molecular Oncology

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24962792%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

8

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21 March 2020

8

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21 March 2020

1495-1507

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24962792%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

NTRK1 fusion in glioblastoma multiforme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Kinase fusions are frequent in Spitz tumours and spitzoid melanomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Tyrosine kinase gene rearrangements in epithelial malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Targeted therapy for NSCLC with driver mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

ALK Rearrangements Are Mutually Exclusive with Mutations in EGFR or KRAS: An Analysis of 1,683 Patients with Non–Small Cell Lung Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Targeted sequencing of cancer-related genes in colorectal cancer using next-generation sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Recurrent R-spondin fusions in colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Nerve growth factor and the physiology of pain: lessons from congenital insensitivity to pain with anhidrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Comprehensive molecular characterization of human colon and rectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

The generation of purinome-targeted libraries as a means to diversify ATP-mimetic chemical classes for lead finding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

ROS1 rearrangements define a unique molecular class of lung cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

NMS-P937, a 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivative as potent and selective Polo-like kinase 1 inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Rearrangements of NTRK1 gene in papillary thyroid carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Treatment in advanced colorectal cancer: what, when and how?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Mutational analysis of the tyrosine kinome in colorectal cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Neurotrophin signal transduction in the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

A sequence analysis of the genomic regions involved in the rearrangements between TPM3 and NTRK1 genes producing TRK oncogenes in papillary thyroid carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Predicting coiled coils from protein sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Human trk oncogenes activated by point mutation, in-frame deletion, and duplication of the tyrosine kinase domain

1 reference

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9 September 2017

TRK-T1 is a novel oncogene formed by the fusion of TPR and TRK genes in human papillary thyroid carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

9 September 2017

Cell line identity finding by fingerprinting, an optimized resource for short tandem repeat profile authentication

1 reference

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9 September 2017

The nerve growth factor 35 years later

1 reference

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14 September 2017

Specific TrkA survival signals interfere with different apoptotic pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528583

25 September 2017

Functions of the neurotrophins during nervous system development: what the knockouts are teaching us.

1 reference

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25 September 2017

Signal transduction by the neurotrophin receptors

1 reference

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25 September 2017

Characterization of a newly identified ETV6-NTRK3 fusion transcript in acute myeloid leukemia

1 reference

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17 June 2018

A novel NTRK1 mutation associated with congenital insensitivity to pain with anhidrosis

1 reference

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17 June 2018

Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice.

1 reference

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17 June 2018

Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies

1 reference

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21 August 2018

Chromosome 1 rearrangements involving the genes TPR and NTRK1 produce structurally different thyroid-specific TRK oncogenes

1 reference

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21 August 2018

Colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.06.001

21 January 2018

Autophosphorylation of activation loop tyrosines regulates signaling by the TRK nerve growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/24962792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophic factors and their receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/24962792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ETV6 Rearrangements in Patients with Infantile Fibrosarcomas and Congenital Mesoblastic Nephromas by Fluorescence In Situ Hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/24962792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MOLONC.2014.06.001

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24962792%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24962792%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24962792%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

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