(Q38999071)

8 September 2017

title

Aristolochic acid-induced apoptosis and G2 cell cycle arrest depends on ROS generation and MAP kinases activation (English)

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8 September 2017

Victor Romanov

1

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8 September 2017

Terry C Whyard

2

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8 September 2017

Wayne C Waltzer

3

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8 September 2017

Arthur P Grollman

4

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8 September 2017

Thomas Rosenquist

5

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8 September 2017

publication date

4 May 2014

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8 September 2017

published in

Archives of Toxicology

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8 September 2017

volume

89

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8 September 2017

issue

1

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8 September 2017

page(s)

47-56

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Cell cycle regulation by p38 MAP kinases

8 September 2017

cites work

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EAPP modulates the activity of p21 and Chk2.

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Analyses of DNA adducts formed by ochratoxin A and aristolochic acid in patients with Chinese herbs nephropathy

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DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis studies in mammalian cells

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ERK implication in cell cycle regulation

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Induction of urothelial proliferation in rats by aristolochic acid through cell cycle progression via activation of cyclin D1/cdk4 and cyclin E/cdk2.

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Aristolochic acid-induced cell cycle G1 arrest in human urothelium SV-HUC-1 cells.

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Microarray analysis reveals the inhibition of nuclear factor-kappa B signaling by aristolochic acid in normal human kidney (HK-2) cells

21 January 2018

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Inhibition of renal NQO1 activity by dicoumarol suppresses nitroreduction of aristolochic acid I and attenuates its nephrotoxicity.

21 January 2018

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MAPK cell-cycle regulation in Saccharomyces cerevisiae and Candida albicans

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Possible role of mtDNA depletion and respiratory chain defects in aristolochic acid I-induced acute nephrotoxicity

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Aristolochia manshuriensis Kom inhibits adipocyte differentiation by regulation of ERK1/2 and Akt pathway

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Aristolochic acid I-induced DNA damage and cell cycle arrest in renal tubular epithelial cells in vitro.

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Differential cytotoxic effects of denitroaristolochic acid II and aristolochic acids on renal epithelial cells

21 January 2018

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Evaluation of the cytotoxicity and genotoxicity of aristolochic acid I - a component of Aristolochiaceae plant extracts used in homeopathy

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Mitogen-activated signaling and cell cycle regulation in airway smooth muscle

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Aristolochic acid induces proximal tubule apoptosis and epithelial to mesenchymal transformation

21 January 2018

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Role of mitochondrial permeability transition in human renal tubular epithelial cell death induced by aristolochic acid.

21 January 2018

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Inhibition of p38-MAPK potentiates cisplatin-induced apoptosis via GSH depletion and increases intracellular drug accumulation in growth-arrested kidney tubular epithelial cells

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21 January 2018

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JNK-dependent AP-1 activation is required for aristolochic acid-induced TGF-β1 synthesis in human renal proximal epithelial cells.

21 January 2018

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21 January 2018

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Involvement of p38 MAPK phosphorylation and nitrate formation in aristolochic acid-mediated antiplatelet activity

21 January 2018

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Aristolochic acid induces apoptosis of human umbilical vein endothelial cells in vitro by suppressing PI3K/Akt signaling pathway

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Selective toxicity of aristolochic acids I and II.

21 January 2018

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Biotransformation enzymes in development of renal injury and urothelial cancer caused by aristolochic acid

21 January 2018

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Contribution of biotransformation enzymes to the development of renal injury and urothelial cancer caused by aristolochic acid: urgent questions, difficult answers

21 January 2018

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21 January 2018

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Combined experimental and computational analysis of DNA damage signaling reveals context-dependent roles for Erk in apoptosis and G1/S arrest after genotoxic stress

21 January 2018

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Hepatic cytochrome P450s metabolize aristolochic acid and reduce its kidney toxicity

21 January 2018

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Cysteinyl leukotrienes synthesis is involved in aristolochic acid I-induced apoptosis in renal proximal tubular epithelial cells

21 January 2018

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Aristolochic acid I induced oxidative DNA damage associated with glutathione depletion and ERK1/2 activation in human cells

21 January 2018

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Aristolochic acid I induced autophagy extenuates cell apoptosis via ERK 1/2 pathway in renal tubular epithelial cells

21 January 2018

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Activation of p53 promotes renal injury in acute aristolochic acid nephropathy

21 January 2018

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Endoplasmic reticulum stress mediates aristolochic acid I-induced apoptosis in human renal proximal tubular epithelial cells

21 January 2018

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10.1007/S00204-014-1249-Z

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

8 September 2017

1049714173

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1 reference