(Q39225712)

10 September 2017

Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity (English)

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10 September 2017

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Parman T

1

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10 September 2017

Wiley MJ

series ordinal

2

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10 September 2017

Wells PG

series ordinal

3

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10 September 2017

language of work or name

English

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publication date

1 May 1999

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10 September 2017

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10 September 2017

5

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10 September 2017

582-585

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10 September 2017

5

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https://scigraph.springernature.com/pub.10.1038/8466

10 September 2017

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cites work

A short history of thalidomide embryopathy

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7 January 2021

Thalidomide, a current teratogen in South America

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7 January 2021

Proposed mechanisms of action in thalidomide embryopathy

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7 January 2021

Biochemical toxicology of chemical teratogenesis

1 reference

7 January 2021

Free radical intermediates of phenytoin and related teratogens. Prostaglandin H synthase-catalyzed bioactivation, electron paramagnetic resonance spectrometry, and photochemical product analysis.

1 reference

7 January 2021

DNA oxidation as a potential molecular mechanism mediating drug-induced birth defects: phenytoin and structurally related teratogens initiate the formation of 8-hydroxy-2'-deoxyguanosine in vitro and in vivo in murine maternal hepatic and embryonic

1 reference

7 January 2021

Evidence for embryonic prostaglandin H synthase-catalyzed bioactivation and reactive oxygen species-mediated oxidation of cellular macromolecules in phenytoin and benzo[a]pyrene teratogenesis

1 reference

7 January 2021

Thalidomide: lack of mutagenic activity across phyla and genetic endpoints.

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7 January 2021

Thalidomide teratogenesis: evidence for a toxic arene oxide metabolite

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7 January 2021

Interaction of [glutarimide-2-14C]-thalidomide with rat embryonic DNA in vivo

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7 January 2021

Never-ending tales of the mode of the teratogenic action of thalidomide

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7 January 2021

Teratogen metabolism: thalidomide activation is mediated by cytochrome P-450

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7 January 2021

Induction of morphological differentiation in the human leukemic cell line K562 by exposure to thalidomide metabolites

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7 January 2021

Relationship between teratogeny and structure in the thalidomide field

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7 January 2021

Cytochrome P450 in human fetal liver: significance and fetal-specific expression

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7 January 2021

Characterization of a novel cytochrome P450 from the transformable cell line, C3H/10T1/2

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7 January 2021

Maternal administration of superoxide dismutase and catalase in phenytoin teratogenicity

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7 January 2021

Identifiers

DOI

10.1038/8466

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10 September 2017

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