(Q39226854)

10 September 2017

Alternative variables in drug discovery: promises and challenges (English)

1 reference

10 September 2017

1 reference

Cele Abad-Zapatero

1

1 reference

10 September 2017

Edmund J Champness

series ordinal

2

1 reference

10 September 2017

Matthew D Segall

series ordinal

3

1 reference

10 September 2017

1 April 2014

1 reference

Future Medicinal Chemistry

10 September 2017

1 reference

10 September 2017

6

1 reference

10 September 2017

577-593

1 reference

10 September 2017

5

1 reference

Molecular property filters describing pharmacokinetics and drug binding

10 September 2017

1 reference

The maximal affinity of ligands

21 January 2018

1 reference

Ligand efficiency: a useful metric for lead selection

21 January 2018

1 reference

Ligand efficiency indices as guideposts for drug discovery.

21 January 2018

1 reference

Ligand efficiency indices for an effective mapping of chemico-biological space: the concept of an atlas-like representation.

21 January 2018

1 reference

BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities

21 January 2018

1 reference

ChEMBL: a large-scale bioactivity database for drug discovery

21 January 2018

1 reference

Applying medicinal chemistry transformations and multiparameter optimization to guide the search for high-quality leads and candidates.

21 January 2018

1 reference

Ligand efficiency indices for effective drug discovery

21 January 2018

1 reference

Ligand Efficiency Indices (LEIs): More than a Simple Efficiency Yardstick

21 January 2018

1 reference

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

Ligand efficiency and fragment-based drug discovery

21 January 2018

1 reference

Using the Golden Triangle to optimize clearance and oral absorption

21 January 2018

1 reference

Multi-parameter optimization: identifying high quality compounds with a balance of properties

21 January 2018

1 reference

Beyond profiling: using ADMET models to guide decisions

21 January 2018

1 reference

Systematic variation in mRNA 3'-processing signals during mouse spermatogenesis

21 January 2018

1 reference

Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties

21 January 2018

1 reference

Drug Guru: a computer software program for drug design using medicinal chemistry rules.

21 January 2018

1 reference

Automatic QSAR modeling of ADME properties: blood-brain barrier penetration and aqueous solubility.

21 January 2018

1 reference

Identifying Important Risk Factors for Survival in Kidney Graft Failure Patients Using Random Survival Forests

21 January 2018

1 reference

The role of ligand efficiency metrics in drug discovery.

21 January 2018

1 reference

Setting expectations in molecular optimizations: Strengths and limitations of commonly used composite parameters

21 January 2018

1 reference

Improving the plausibility of success with inefficient metrics

21 January 2018

1 reference

Bayesian learning and the psychology of rule induction

21 January 2018

1 reference

Considering the impact drug-like properties have on the chance of success

21 January 2018

1 reference

Predicting synthetic accessibility: application in drug discovery and development

21 January 2018

1 reference

An analysis of the binding efficiencies of drugs and their leads in successful drug discovery programs

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.4155/FMC.14.16

1 reference

release_qp4kl4damjehxemychcw37hqnq

10 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qp4kl4damjehxemychcw37hqnq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference