(Q39445499)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10207063%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

title

Reactivation of mutant p53 through interaction of a C-terminal peptide with the core domain (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10207063%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10207063%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

Klas Wiman

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10207063%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

author name string

L Ryabchenko

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10207063%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

E Jansson

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10207063%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

V Iotsova

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10207063%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

language of work or name

English

0 references

publication date

1 May 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10207063%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

4 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10207063%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10207063%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10207063%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

page(s)

3395-3402

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10207063%20AND%20SRC:MED&resulttype=core&format=json

Identification of an additional negative regulatory region for p53 sequence-specific DNA binding

4 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

The single-stranded DNA end binding site of p53 coincides with the C-terminal regulatory region.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

12 September 2017

p53: puzzle and paradigm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

Regulation of specific DNA binding by p53: evidence for a role for O-glycosylation and charged residues at the carboxy-terminus

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

High-resolution structure of the oligomerization domain of p53 by multidimensional NMR

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

Allosteric activation of latent p53 tetramers

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

Solution structure of the tetrameric minimum transforming domain of p53

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

Oncogenic forms of p53 inhibit p53-regulated gene expression

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

Regulation of the specific DNA binding function of p53

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

p53: a transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

Activation of the cryptic DNA binding function of mutant forms of p53.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

A C-terminal alpha-helix plus basic region motif is the major structural determinant of p53 tetramerization

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

p53 domains: identification and characterization of two autonomous DNA-binding regions.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

Small peptides activate the latent sequence-specific DNA binding function of p53.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84132

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

21 August 2018

1 reference

12 December 2020

Structure-based rescue of common tumor-derived p53 mutants

1 reference

12 December 2020

Restoration of the transcription activation function to mutant p53 in human cancer cells

1 reference

12 December 2020

Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.19.5.3395

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10207063%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10207063%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

PubMed publication ID

10207063

1 reference