(Q39555328)

English

KX-01, a novel Src kinase inhibitor directed toward the peptide substrate site, synergizes with tamoxifen in estrogen receptor α positive breast cancer

scientific article published on 21 April 2011

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scholarly article

1 reference

Europe PubMed Central

13 September 2017

KX-01, a novel Src kinase inhibitor directed toward the peptide substrate site, synergizes with tamoxifen in estrogen receptor α positive breast cancer (English)

1 reference

Europe PubMed Central

13 September 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Muralidharan Anbalagan

1

1 reference

Europe PubMed Central

13 September 2017

Latonya Carrier

2

1 reference

Europe PubMed Central

13 September 2017

Seth Glodowski

3

1 reference

Europe PubMed Central

13 September 2017

David Hangauer

4

1 reference

Europe PubMed Central

13 September 2017

Bin Shan

5

1 reference

Europe PubMed Central

13 September 2017

Brian G Rowan

6

1 reference

Europe PubMed Central

13 September 2017

language of work or name

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publication date

21 April 2011

1 reference

Europe PubMed Central

13 September 2017

Breast Cancer Research and Treatment

1 reference

Europe PubMed Central

13 September 2017

132

1 reference

Europe PubMed Central

13 September 2017

391-409

1 reference

Europe PubMed Central

13 September 2017

2

1 reference

Europe PubMed Central

13 September 2017

https://scigraph.springernature.com/pub.10.1007/s10549-011-1513-3

0 references

Recent advances and current controversies in the management of DCIS of the breast

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Tamoxifen treatment for breast cancer and risk of endometrial cancer: a case-control study

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Randomized dose-ranging trial of tamoxifen at low doses in hormone replacement therapy users.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Is expression or activation of Src kinase associated with cancer-specific survival in ER-, PR- and HER2-negative breast cancer patients?

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Src as a therapeutic target in anti-hormone/anti-growth factor-resistant breast cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

SRC kinase and mitogen-activated protein kinases in the progression from normal to malignant endometrium

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

The Src kinase pathway promotes tamoxifen agonist action in Ishikawa endometrial cells through phosphorylation-dependent stabilization of estrogen receptor (alpha) promoter interaction and elevated steroid receptor coactivator 1 activity

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Neoadjuvant percutaneous 4-hydroxytamoxifen decreases breast tumoral cell proliferation: a prospective controlled randomized study comparing three doses of 4-hydroxytamoxifen gel to oral tamoxifen

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on SRC kinase for survival

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

c-Src-null mice exhibit defects in normal mammary gland development and ERalpha signaling

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Potentiation of estrogen receptor activation function 1 (AF-1) by Src/JNK through a serine 118-independent pathway

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Combination of methylselenocysteine with tamoxifen inhibits MCF-7 breast cancer xenografts in nude mice through elevated apoptosis and reduced angiogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Combined Src and aromatase inhibition impairs human breast cancer growth in vivo and bypass pathways are activated in AZD0530-resistant tumors

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Regulation of Cdc2 activity by phosphorylation at T14/Y15

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Novel intestinal splice variants of RNA-binding protein CUGBP2: isoform-specific effects on mitotic catastrophe.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Differential phosphorylation of Cdc25C phosphatase in mitosis

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

cdc25 is one of the MPM-2 antigens involved in the activation of maturation-promoting factor

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Dual targeting of Src and ER prevents acquired antihormone resistance in breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Elevated Src kinase activity attenuates Tamoxifen response in vitro and is associated with poor prognosis clinically

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Cooperative action of tamoxifen and c-Src inhibition in preventing the growth of estrogen receptor-positive human breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Estrogen rapid action via protein complex formation involving ERalpha and Src.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Steroid receptor phosphorylation: a key modulator of multiple receptor functions

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Phosphorylation of serine-167 on the human oestrogen receptor is important for oestrogen response element binding and transcriptional activation

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Phosphorylation of the human estrogen receptor by mitogen-activated protein kinase and casein kinase II: consequence on DNA binding

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Requirement for Src family protein tyrosine kinases in G2 for fibroblast cell division

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Role of c-Src in human MCF7 breast cancer cell tumorigenesis

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

A non-catalytic function of the Src family tyrosine kinases controls prolactin-induced Jak2 signaling.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Novel noncatalytic role for caspase-8 in promoting SRC-mediated adhesion and Erk signaling in neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Tamoxifen and TRAIL synergistically induce apoptosis in breast cancer cells.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Regulation of angiogenesis and vascular permeability by Src family kinases: opportunities for therapeutic treatment of solid tumors.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Effects of oestradiol and tamoxifen on VEGF, soluble VEGFR-1, and VEGFR-2 in breast cancer and endothelial cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Src Signaling Regulates Completion of Abscission in Cytokinesis through ERK/MAPK Activation at the Midbody

1 reference

https://api.crossref.org/works/10.1007%2FS10549-011-1513-3

21 January 2018

Identifiers

10.1007/S10549-011-1513-3

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

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