(Q39562595)

English

DICKKOPF-4 activates the noncanonical c-Jun-NH2 kinase signaling pathway while inhibiting the Wnt-canonical pathway in human renal cell carcinoma

scientific article published on 8 November 2010

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scholarly article

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

DICKKOPF-4 activates the noncanonical c-Jun-NH2 kinase signaling pathway while inhibiting the Wnt-canonical pathway in human renal cell carcinoma (English)

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

3

object named as

Shahana Majid

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

10

object named as

Rajvir Dahiya

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

author name string

Hiroshi Hirata

1

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

Yuji Hinoda

2

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

Yi Chen

4

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

Mohd S Zaman

5

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

Koji Ueno

6

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

Koichi Nakajima

7

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

Z Laura Tabatabai

8

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

Nobuhisa Ishii

9

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Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

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publication date

8 November 2010

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Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

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Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

117

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17 June 2018

http://europepmc.org/abstract/PMC/5871344

1649-1660

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http://europepmc.org/abstract/PMC/5871344

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1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

Role of secreted frizzled-related protein 3 in human renal cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Sustained c-Jun-NH2-kinase activity promotes epithelial-mesenchymal transition, invasion, and survival of breast cancer cells by regulating extracellular signal-regulated kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Activation of the non-canonical Dvl-Rac1-JNK pathway by Frizzled homologue 10 in human synovial sarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Dickkopf-4 is frequently down-regulated and inhibits growth of colorectal cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Blockade of the RhoA-JNK-c-Jun-MMP2 cascade by atorvastatin reduces osteosarcoma cell invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Cancer statistics, 2008

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Invasive ability of human renal cell carcinoma cell line Caki-2 is accelerated by gamma-aminobutyric acid, via sustained activation of ERK1/2 inducible matrix metalloproteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

WNT signaling pathway and stem cell signaling network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Wnt signaling pathway in mammary gland development and carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

REIC/Dkk-3 as a potential gene therapeutic agent against human testicular cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Function and biological roles of the Dickkopf family of Wnt modulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Dickkopf-1 induced apoptosis in human placental choriocarcinoma is independent of canonical Wnt signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of c-Jun-NH2-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Dickkopf-1 antagonizes Wnt signaling independent of beta-catenin in human mesothelioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Inhibition of MKP-1 expression potentiates JNK related apoptosis in renal cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Secreted antagonists of the Wnt signalling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

Natural history and therapy of metastatic renal cell carcinoma: the role of interleukin-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

22 June 2018

DICKKOPF-4 and -2 genes are upregulated in human colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

21 August 2018

pVHL co-ordinately regulates CXCR4/CXCL12 and MMP2/MMP9 expression in human clear-cell renal cell carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

21 August 2018

Wnt antagonist family genes as biomarkers for diagnosis, staging, and prognosis of renal cell carcinoma using tumor and serum DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

21 August 2018

c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

21 August 2018

C-jun activation in acquired cystic kidney disease and renal cell carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

21 August 2018

JNK and ROKalpha function in the noncanonical Wnt/RhoA signaling pathway to regulate Xenopus convergent extension movements.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5871344

21 August 2018

REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinases 1 and 2 correlate with poor prognostic variables in renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional significance of Wnt inhibitory factor-1 gene in kidney cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/CNCR.25666

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

release_bz3kru73jnhtdjgftmgxltk7sq

0 references

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

1 reference

Europe PubMed Central

17 June 2018

http://europepmc.org/abstract/PMC/5871344

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