(Q39571848)

13 September 2017

mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways (English)

1 reference

13 September 2017

1 reference

1 reference

11

B Mark Evers

1 reference

13 September 2017

Pat Gulhati

1

1 reference

13 September 2017

Kanika A Bowen

2

1 reference

13 September 2017

Jianyu Liu

3

1 reference

13 September 2017

Payton D Stevens

4

1 reference

13 September 2017

Piotr G Rychahou

5

1 reference

13 September 2017

Min Chen

6

1 reference

13 September 2017

Eun Y Lee

7

1 reference

13 September 2017

Heidi L Weiss

8

1 reference

13 September 2017

Kathleen L O'Connor

9

1 reference

13 September 2017

Tianyan Gao

10

1 reference

13 September 2017

language of work or name

English

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publication date

23 March 2011

1 reference

13 September 2017

1 reference

13 September 2017

71

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13 September 2017

9

1 reference

13 September 2017

3246-3256

1 reference

13 September 2017

Global cancer statistics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

mTOR Complex Component Rictor Interacts with PKCζ and Regulates Cancer Cell Metastasis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Rapamycin regulates endothelial cell migration through regulation of the cyclin-dependent kinase inhibitor p27Kip1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

PTEN loss induces epithelial--mesenchymal transition in human colon cancer cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

New insights of epithelial-mesenchymal transition in cancer metastasis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Rapamycin inhibits F-actin reorganization and phosphorylation of focal adhesion proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Cell size and invasion in TGF-beta-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Defining the role of mTOR in cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Epithelial-mesenchymal transitions in tumour progression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

RhoA function in lamellae formation and migration is regulated by the alpha6beta4 integrin and cAMP metabolism

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Rho GTPases and the actin cytoskeleton

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Targeted molecular therapy of the PI3K pathway: therapeutic significance of PI3K subunit targeting in colorectal carcinoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

The phosphatidylinositol 3'-kinase p85alpha gene is an oncogene in human ovarian and colon tumors.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085654

Expression of cytokeratins 7 and 20 in carcinomas of the gastrointestinal tract

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21430067

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Predictors of survival after curative resection of carcinoma of the colon and rectum

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21430067

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-10-4058

1 reference

release_aodwofefujgf5bgbdzok47ozoa

13 September 2017

0 references

1 reference

13 September 2017

PubMed publication ID

21430067

1 reference