(Q39575132)

English

Molecular mechanism governing heme signaling in yeast: a higher-order complex mediates heme regulation of the transcriptional activator HAP1.

scientific article published on July 1998

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scholarly article

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12 November 2019

Molecular mechanism governing heme signaling in yeast: a higher-order complex mediates heme regulation of the transcriptional activator HAP1 (English)

1 reference

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12 November 2019

1

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12 November 2019

author name string

A Hach

2

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12 November 2019

C Wang

3

1 reference

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12 November 2019

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publication date

1 July 1998

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12 November 2019

Molecular and Cellular Biology

1 reference

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12 November 2019

18

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12 November 2019

3819-3828

1 reference

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12 November 2019

7

1 reference

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12 November 2019

In vivo analysis of the Hsp90 cochaperone Sti1 (p60)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

The C6 zinc cluster dictates asymmetric binding by HAP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Inhibition of tartrate-resistant acid phosphatase gene expression by hemin and protoporphyrin IX. Identification of a hemin-responsive inhibitor of transcription.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

A positive control mutant of the transcription activator protein FIS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Mutational analysis of the DNA binding, dimerization, and transcriptional activation domains of MEF2C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Antibody-promoted dimerization bypasses the regulation of DNA binding by the heme domain of the yeast transcriptional activator HAP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Evidence for an interaction between the CYP1(HAP1) activator and a cellular factor during heme-dependent transcriptional regulation in the yeast Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Regulation by heme of mitochondrial protein transport through a conserved amino acid motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Determinants of binding-site specificity among yeast C6 zinc cluster proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

HAP1 is nuclear but is bound to a cellular factor in the absence of heme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Positive control mutations in the MyoD basic region fail to show cooperative DNA binding and transcriptional activation in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Evidence that TUP1/SSN6 has a positive effect on the activity of the yeast activator HAP1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Crystal structure of a PPR1-DNA complex: DNA recognition by proteins containing a Zn2Cys6 binuclear cluster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

The yeast activator HAP1--a GAL4 family member--binds DNA in a directly repeated orientation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Hormone-dependent transactivation by the human androgen receptor is regulated by a dnaJ protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Solution structure of the Kluyveromyces lactis LAC9 Cd2 Cys6 DNA-binding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Evidence for translational regulation of the activator of general amino acid control in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Inducible transcription of five globin genes in K562 human leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Yeast HAP1 activator binds to two upstream activation sites of different sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

CYP1 (HAP1) regulator of oxygen-dependent gene expression in yeast. I. Overall organization of the protein sequence displays several novel structural domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Regulation of cytochrome P-450b/e gene expression by a heme- and phenobarbitone-modulated transcription factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Haem as a multifunctional regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

The Saccharomyces cerevisiae PUT3 activator protein associates with proline-specific upstream activation sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Identification and characterization of HAP4: a third component of the CCAAT-bound HAP2/HAP3 heteromer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Analysis of constitutive and noninducible mutations of the PUT3 transcriptional activator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Regulation of gene expression by oxygen in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

DNA recognition by GAL4: structure of a protein-DNA complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Hold 'em and fold 'em: chaperones and signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

14 September 2017

Heme binds to a short sequence that serves a regulatory function in diverse proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

25 September 2017

Iron protoporphyrin IX (hemin) but not tin or zinc protoporphyrin IX can stimulate gene expression in K562 cells from enhancer elements containing binding sites for NF-E2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

25 September 2017

Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

25 September 2017

Transcriptional regulator Leu3 of Saccharomyces cerevisiae: separation of activator and repressor functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

15 June 2018

Functional dissection and sequence of yeast HAP1 activator.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

15 June 2018

Reduced levels of hsp90 compromise steroid receptor action in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

15 June 2018

The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108966

15 June 2018

Regulation of vascular endothelial growth factor in cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the protein chaperone YDJ1 in establishing Hsp90-mediated signal transduction pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple domains mediate heme control of the yeast activator HAP1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Synthesis of Catalases and Iso-1-cytochrome c in Saccharomyces cerevisiae by Glucose, Oxygen and Heme

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of globin gene expression in the human erythroid cell line K562

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinctly regulated tandem upstream activation sites mediate catabolite repression of the CYC1 gene of S. cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations that alter transcriptional activation but not DNA binding in the zinc finger of yeast activator HAPI

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of unactivated progesterone receptor and identification of novel receptor-associated proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Farnesylation of YDJ1p is required for function at elevated growth temperatures in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HAP1 positive control mutants specific for one of two binding sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.18.7.3819

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632766%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632766%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632766%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

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