(Q39662076)

English

Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition

scientific article published on 30 August 2010

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scholarly article

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Europe PubMed Central

13 September 2017

Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition (English)

1 reference

Europe PubMed Central

13 September 2017

1 reference

based on heuristic

inferred from title

apoptotic process

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based on heuristic

inferred from title

author name string

C Ji

1

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Europe PubMed Central

13 September 2017

B Yang

2

1 reference

Europe PubMed Central

13 September 2017

Y-L Yang

3

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Europe PubMed Central

13 September 2017

S-H He

4

1 reference

Europe PubMed Central

13 September 2017

D-S Miao

5

1 reference

Europe PubMed Central

13 September 2017

L He

6

1 reference

Europe PubMed Central

13 September 2017

Z-G Bi

7

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13 September 2017

language of work or name

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publication date

30 August 2010

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13 September 2017

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Europe PubMed Central

13 September 2017

29

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13 September 2017

6557-6568

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50

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13 September 2017

https://scigraph.springernature.com/pub.10.1038/onc.2010.379

0 references

AMP-activated protein kinase in the heart: role during health and disease

1 reference

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Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals

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AMP-activated protein kinase contributes to UV- and H2O2-induced apoptosis in human skin keratinocytes

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The AMP-activated protein kinase cascade--a unifying system for energy control

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Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: a crucial role of AMPK and mTOR pathways.

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TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

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TSC2 mediates cellular energy response to control cell growth and survival

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Effects of adenosine on myocardial glucose and palmitate metabolism after transient ischemia: role of 5'-AMP-activated protein kinase

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

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Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells

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AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

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Compound K induces apoptosis via CAMK-IV/AMPK pathways in HT-29 colon cancer cells

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Regulation of ceramide production and apoptosis

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Combined cytotoxic action of paclitaxel and ceramide against the human Tu138 head and neck squamous carcinoma cell line

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Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib.

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Mitochondrial and nuclear p53 localization in cardiomyocytes: redox modulation by doxorubicin (Adriamycin)?

1 reference

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Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress.

1 reference

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Inhibition of mTOR in combination with doxorubicin in an experimental model of hepatocellular carcinoma

1 reference

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Killing tumours by ceramide-induced apoptosis: a critique of available drugs

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De novo ceramide synthesis is responsible for the anti-tumor properties of camptothecin and doxorubicin in follicular thyroid carcinoma.

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Rapamycin inhibits doxorubicin-induced NF-kappaB/Rel nuclear activity and enhances the apoptosis of melanoma cells

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Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome

1 reference

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AMPK in Health and Disease

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AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling

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Thyroid hormone activates adenosine 5'-monophosphate-activated protein kinase via intracellular calcium mobilization and activation of calcium/calmodulin-dependent protein kinase kinase-beta

1 reference

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Activation of AMP-activated protein kinase by kainic acid mediates brain-derived neurotrophic factor expression through a NF-kappaB dependent mechanism in C6 glioma cells

1 reference

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Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha

1 reference

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Rapamycin inhibits cell growth by induction of apoptosis on hepatocellular carcinoma cells in vitro

1 reference

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31 March 2020

Acute doxorubicin cardiotoxicity is associated with p53-induced inhibition of the mammalian target of rapamycin pathway

1 reference

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Cytotoxic effects of sphingolipids as single or multi-modality agents on human melanoma and soft tissue sarcoma in vitro.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Anthracyclines in the treatment of cancer. An overview

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/ONC.2010.379

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

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