(Q39703974)

14 September 2017

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title

The impact of genetic engineering on the commercial production of antibiotics by Streptomyces and related bacteria (English)

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14 September 2017

C R Hutchinson

1

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14 September 2017

publication date

1 September 1987

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Applied Biochemistry and Biotechnology

14 September 2017

published in

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14 September 2017

volume

16

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14 September 2017

page(s)

169-190

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Transduction of Auxotrophic Markers in a Chloramphenicol-producing Strain of Streptomyces

14 September 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FBF02798365

Efficient plasmid transformation of Streptomyces ambofaciens and Streptomyces fradiae protoplasts

21 January 2018

1 reference

12 December 2020

Transductional analysis of chloramphenicol biosynthesis genes in Streptomyces venezuelae

1 reference

12 December 2020

Isolation, sequence determination and expression in Escherichia coli of the isopenicillin N synthetase gene from Cephalosporium acremonium

1 reference

12 December 2020

Nucleotide sequence of a streptomycete aminoglycoside phosphotransferase gene and its relationship to phosphotransferases encoded by resistance plasmids

1 reference

12 December 2020

Phage-mediated cloning of bldA, a region involved in Streptomyces coelicolor morphological development, and its analysis by genetic complementation

1 reference

12 December 2020

pIJ101, a multi-copy broad host-range Streptomyces plasmid: Functional analysis and development of DNA cloning vectors

1 reference

12 December 2020

Analysis of the role of cysteine residues in isopenicillin N synthetase activity by site-directed mutagenesis

1 reference

12 December 2020

Giant linear plasmids in Streptomyces which code for antibiotic biosynthesis genes

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12 December 2020

Control of antibiotic biosynthesis

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12 December 2020

Cloning and heterologous expression of a gene cluster for the biosynthesis of tetracenomycin C, the anthracycline antitumor antibiotic of Streptomyces glaucescens

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12 December 2020

Cloning and expression of a p-aminobenzoic acid synthetase gene of the candicidin-producing Streptomyces griseus.

1 reference

12 December 2020

Construction and application of a promoter-probe plasmid that allows chromogenic identification in Streptomyces lividans

1 reference

12 December 2020

alpha-Amylase gene of Streptomyces limosus: nucleotide sequence, expression motifs, and amino acid sequence homology to mammalian and invertebrate alpha-amylases

1 reference

12 December 2020

Activity of a Streptomyces transcriptional terminator in Escherichia coli

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12 December 2020

Cloning genes for the biosynthesis of a macrolide antibiotic

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12 December 2020

Cloning and expression of an extracellular-agarase from Streptomyces coelicolor A3(2) in Streptomyces lividans 66

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12 December 2020

Streptomyces lividans RNA polymerase recognizes and uses Escherichia coli transcriptional signals

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12 December 2020

The glycerol utilization operon of Streptomyces coelicolor: genetic mapping of gyl mutations and the analysis of cloned gyl DNA

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12 December 2020

Optimization of gene expression in Streptomyces lividans by a transcription terminator

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12 December 2020

Mutational cloning in Streptomyces and the isolation of antibiotic production genes

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12 December 2020

Cloning and expression of the isopenicillin N synthetase gene from Penicillium chrysogenum

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12 December 2020

Molecular cloning and characterization of the Streptomyces hygroscopicus alpha-amylase gene

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12 December 2020

The glucose kinase gene of Streptomyces coelicolor and its use in selecting spontaneous deletions for desired regions of the genome

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12 December 2020

Plasmid and phage vectors for gene cloning and analysis in Streptomyces

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12 December 2020

Integrated DNA sequences in three streptomycetes form related autonomous plasmids after transfer to Streptomyces lividans.

1 reference

12 December 2020

Structural analysis of plasmid and chromosomal loci involved in site-specific excision and integration of the SLP1 element of Streptomyces coelicolor

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12 December 2020

Cloning and nucleotide sequence of a carbomycin-resistance gene from Streptomyces thermotolerans

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12 December 2020

Replacement of Streptomyces hygroscopicus genomic segments with in vitro altered DNA sequences

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12 December 2020

Cloning of a streptomycin-production gene directing synthesis of N-methyl-L-glucosamine

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12 December 2020

Highly transformable mutants of Streptomyces fradiae defective in several restriction systems

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12 December 2020

Cloning and expression of a Streptomyces cholesterol oxidase gene in Streptomyces lividans with plasmid pIJ702.

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12 December 2020

Primary structure of the Streptomyces R61 extracellular DD-peptidase. 1. Cloning into Streptomyces lividans and nucleotide sequence of the gene

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12 December 2020

Identification of the promoter for a peptide antibiotic biosynthesis gene from Bacillus brevis and its regulation in Bacillus subtilis

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12 December 2020

Nucleotide sequence analysis reveals similarities between proteins determining methylenomycin A resistance in Streptomyces and tetracycline resistance in eubacteria

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12 December 2020

The nucleotide sequence of the tyrosinase gene from Streptomyces antibioticus and characterization of the gene product

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12 December 2020

A 2.6 kb DNA sequence of Streptomyces coelicolor A3(2) which functions as a transposable element.

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12 December 2020

Tn4556, a 6.8-kilobase-pair transposable element of Streptomyces fradiae

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12 December 2020

The Streptomyces plasmid SCP2*: its functional analysis and development into useful cloning vectors.

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12 December 2020

Chromogenic identification of promoters in Streptomyces lividans by using an ampC beta-lactamase promoter-probe vector

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12 December 2020

recA gene of Escherichia coli complements defects in DNA repair and mutagenesis in Streptomyces fradiae JS6 (mcr-6).

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12 December 2020

Relationship of an unstable argG gene to a 5.7-kilobase amplifiable DNA sequence in Streptomyces lividans 66.

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12 December 2020

Negative control for the expression of streptomycin resistance gene from streptomycin-producing Streptomyces griseus

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12 December 2020

Mechanism of increased kanamycin-resistance generated by protoplast regeneration of Streptomyces griseus. II. Mutational gene alteration and gene amplification

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12 December 2020

Mechanism of increased kanamycin-resistance generated by protoplast regeneration of Streptomyces griseus. I. Cloning of a gene segment directing a high level of an aminoglycoside 3-N-acetyltransferase activity

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12 December 2020

RNA polymerase heterogeneity in Streptomyces coelicolor

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12 December 2020

Gene cluster for streptomycin biosynthesis in Streptomyces griseus: nucleotide sequence of three genes and analysis of transcriptional activity

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12 December 2020

Characterization of the promoter, signal sequence, and amino terminus of a secreted beta-galactosidase from "Streptomyces lividans".

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12 December 2020

Cloning of whiG, a gene critical for sporulation of Streptomyces coelicolor A3(2).

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12 December 2020

Genetic mapping, cloning and physiological aspects of the glucose kinase gene of Streptomyces coelicolor

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12 December 2020

Molecular cloning of the whole biosynthetic pathway of a Streptomyces antibiotic and its expression in a heterologous host

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12 December 2020

Physical and genetic analysis of IS110, a transposable element of Streptomyces coelicolor A3(2).

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12 December 2020

Genetics of Actinorhodin Biosynthesis by Streptomyces coelicolor A3(2)

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12 December 2020

Streptomycin-sensitivity in Streptomyces glaucescens is due to deletions comprising the structural gene coding for a specific phosphotransferase

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12 December 2020

Characterisation of the hydroxystreptomycin phosphotransferase gene (sph) of Streptomyces glaucescens: nucleotide sequence and promoter analysis

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12 December 2020

Molecular cloning of an ornithine-activating fragment of the gramicidin S synthetase 2 gene from Bacillus brevis and its expression in Escherichia coli

1 reference

12 December 2020

Shuttle vectors for cloning recombinant DNA in Escherichia coli and Streptomyces griseofuscus C581

1 reference

12 December 2020

Cloning and expression of Mycobacterium bovis BCG DNA in "Streptomyces lividans".

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12 December 2020

Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from Streptomyces clavuligerus

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12 December 2020

Pleiotropic morphological and antibiotic deficiencies result from mutations in a gene encoding a tRNA-like product in Streptomyces coelicolor A3(2).

1 reference

12 December 2020

Excision of chromosomal DNA sequences from Streptomyces coelicolor forms a novel family of plasmids detectable in Streptomyces lividans

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12 December 2020

Molecular cloning and expression of the phenoxazinone synthase gene from Streptomyces antibioticus

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12 December 2020

Plasmids, recombination and chromosome mapping in Streptomyces lividans 66

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12 December 2020

Isolation and characterization of Streptomyces fradiae plasmids which are prophage of the actinophage øSF1

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12 December 2020

The agarase gene (dag A) of Streptomyces coelicolor A3(2): affinity purification and characterization of the cloned gene product

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12 December 2020

Cloning and expression of a Streptomyces plicatus chitinase (chitinase-63) in Escherichia coli

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12 December 2020

Genetic analysis and genome structure in Streptomyces coelicolor

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12 December 2020

A linear DNA plasmid from Streptomyces rochei with an inverted terminal repetition of 614 base pairs

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12 December 2020

Molecular cloning of a xylanase gene from Streptomyces sp. No. 36a and its expression in streptomycetes

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12 December 2020

Homology between Streptomyces genes coding for synthesis of different polyketides used to clone antibiotic biosynthetic genes

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12 December 2020

Two promoters, one inducible and one constitutive, control transcription of the Streptomyces lividans galactose operon

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12 December 2020

Physical and genetic characterisation of the gene cluster for the antibiotic actinorhodin in Streptomyces coelicolor A3(2)

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12 December 2020

Genetic instability and DNA amplification in Streptomyces lividans 66.

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12 December 2020

Involvement of cell impermeability in resistance to macrolides in some producer streptomycetes.

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12 December 2020

Structure of an amplifiable DNA sequence in Streptomyces lividans 66

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12 December 2020

Expression of the Streptomyces enzyme endoglycosidase H in Escherichia coli

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12 December 2020

Nucleotide sequence of the hygromycin B phosphotransferase gene from Streptomyces hygroscopicus

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12 December 2020

Bacillus subtilis phage phi 29 main promoters are efficiently recognized in vivo by the Streptomyces lividans RNA polymerase

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12 December 2020

Synthesis of bovine growth hormone by Streptomyces lividans

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12 December 2020

Spectinomycin resistance and associated DNA amplification in Streptomyces achromogenes subsp. rubradiris

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12 December 2020

Gene organization and structure of the Streptomyces lividans gal operon

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12 December 2020

Multiplication of a DNA fragment in Streptomyces antibioticus--producer of oleandomycin

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12 December 2020

Cloning of the tyrocidine synthetase 1 gene from Bacillus brevis and its expression in Escherichia coli

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12 December 2020

Temperature-sensitive mutants of the Streptomyces plasmid pIJ702

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12 December 2020

Certain chromosomal regions in Streptomyces glaucescens tend to carry amplifications and deletions

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12 December 2020

Self-cloning in Streptomyces griseus of an str gene cluster for streptomycin biosynthesis and streptomycin resistance

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12 December 2020

The minimal replicon of a streptomycete plasmid produces an ultrahigh level of plasmid DNA.

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12 December 2020

Gene cluster for streptomycin biosynthesis in Streptomyces griseus: analysis of a central region including the major resistance gene

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12 December 2020

A new shuttle cosmid vector, pKC505, for streptomycetes: its use in the cloning of three different spiramycin-resistance genes from a Streptomyces ambofaciens library

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12 December 2020

Genetic recombination through protoplast fusion in Streptomyces

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12 December 2020

Cloning and expression of the tyrosinase gene from Streptomyces antibioticus in Streptomyces lividans

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12 December 2020

Cloning and transcription analysis of the entire glycerol utilization (gylABX) operon of Streptomyces coelicolor A3(2) and identification of a closely associated transcription unit

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12 December 2020

Transcriptional regulation of bialaphos biosynthesis in Streptomyces hygroscopicus

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12 December 2020

Cloning and expression of the genetically unstable tyrosinase structural gene from Streptomyces glaucescens

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12 December 2020

Cloning and expression of a tylosin resistance gene from a tylosin-producing strain of Streptomyces fradiae

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12 December 2020

Characterization of Streptomyces promoter sequences using the Escherichia coli galactokinase gene

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12 December 2020

New derivatives of the Streptomyces temperate phage phi C31 useful for the cloning and functional analysis of Streptomyces DNA.

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12 December 2020

Gene Cloning in Streptomyces

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12 December 2020

Expression of a Streptomyces plasmid promoter in Escherichia coli

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12 December 2020

Cloning and characterization of the isopenicillin N synthetase gene mediating the formation of the beta-lactam ring in Aspergillus nidulans.

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12 December 2020

Two promoters from the Streptomyces plasmid pIJ101 and their expression in Escherichia coli

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12 December 2020

The agarase gene (dagA) of Streptomyces coelicolor A3(2): nucleotide sequence and transcriptional analysis.

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12 December 2020

Plasmid transfer in Streptomyces lividans: identification of a kil-kor system associated with the transfer region of pIJ101

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12 December 2020

Characterization and structure of genes for proteases A and B from Streptomyces griseus

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12 December 2020

Cloning and amplified expression in Streptomyces lividans of a gene encoding extracellular beta-lactamase from Streptomyces albus G.

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12 December 2020

Cloning of a pleiotropic gene that positively controls biosynthesis of A-factor, actinorhodin, and prodigiosin in Streptomyces coelicolor A3(2) and Streptomyces lividans

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12 December 2020

Site-specific insertion of biologically functional adventitious genes into the Streptomyces lividans chromosome

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12 December 2020

Genetic determination of methylenomycin synthesis by the SCP1 plasmid of Streptomyces coelicolor A3(2)

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12 December 2020

Cloning of the xylanase gene of Streptomyces lividans

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12 December 2020

Isolation and characterization of Streptomyces lividans mutants deficient in intraplasmid recombination

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12 December 2020

Construction and characterisation of a series of multi-copy promoter-probe plasmid vectors for Streptomyces using the aminoglycoside phosphotransferase gene from Tn5 as indicator.

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12 December 2020

Bacterial protoplast fusion: recombination in fused protoplasts of Streptomyces coelicolor

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12 December 2020

Gene expression in Streptomyces: Construction and application of promoter-probe plasmid vectors in Streptomyces lividans

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12 December 2020

At least three different RNA polymerase holoenzymes direct transcription of the agarase gene (dagA) of Streptomyces coelicolor A3(2)

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12 December 2020

Resistance, regulatory and production genes for the antibiotic methylenomycin are clustered

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12 December 2020

Increased production of aminoglycosides associated with amplified antibiotic resistance genes

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12 December 2020

Identifiers

DOI

10.1007/BF02798365

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14 September 2017

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