(Q39705874)

14 September 2017

title

BACE1 gene promoter single-nucleotide polymorphisms in Alzheimer's disease (English)

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single-nucleotide polymorphism

14 September 2017

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Weihong Song

7

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Robert A. Holt

object named as

Robert A Holt

6

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author name string

Weihui Zhou

1

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14 September 2017

Fang Cai

2

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14 September 2017

Yu Li

3

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14 September 2017

George S Yang

4

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14 September 2017

Kathleen D O'Connor

5

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14 September 2017

publication date

9 May 2010

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Journal of Molecular Neuroscience

14 September 2017

published in

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14 September 2017

volume

42

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14 September 2017

issue

1

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14 September 2017

page(s)

127-133

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Base-calling of automated sequencer traces using phred. I. Accuracy assessment

14 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12031-010-9381-6

Beta-secretase activity increases with aging in human, monkey, and mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-010-9381-6

Consed: a graphical tool for sequence finishing

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12031-010-9381-6

Oxidative damage is the earliest event in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-010-9381-6

Crystallization of glycosylated human BACE protease domain expressed in Trichoplusia ni.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-010-9381-6

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

21 January 2018

1 reference

12 December 2020

Purification and cloning of amyloid precursor protein beta-secretase from human brain

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12 December 2020

Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity

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12 December 2020

The BACE gene: genomic structure and candidate gene study in late-onset Alzheimer's disease.

1 reference

12 December 2020

Human BACE forms dimers and colocalizes with APP.

1 reference

12 December 2020

Association study between Alzheimer's disease and genes involved in Abeta biosynthesis, aggregation and degradation: suggestive results with BACE1.

1 reference

12 December 2020

The 1239G/C polymorphism in exon 5 of BACE1 gene may be associated with sporadic Alzheimer's disease in Chinese Hans

1 reference

12 December 2020

Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

1 reference

12 December 2020

The low density lipoprotein receptor-related protein (LRP) is a novel beta-secretase (BACE1) substrate.

1 reference

12 December 2020

Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation

1 reference

12 December 2020

Functional characterization of the 5' flanking region of the BACE gene: identification of a 91 bp fragment involved in basal level of BACE promoter expression

1 reference

12 December 2020

Degradation of BACE by the ubiquitin-proteasome pathway

1 reference

12 December 2020

BACE (beta-secretase) modulates the processing of APLP2 in vivo

1 reference

12 December 2020

Endoproteolysis of beta-secretase (beta-site amyloid precursor protein-cleaving enzyme) within its catalytic domain. A potential mechanism for regulation

1 reference

12 December 2020

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

1 reference

12 December 2020

The gene encoding DRAP (BACE2), a glycosylated transmembrane protein of the aspartic protease family, maps to the down critical region

1 reference

12 December 2020

Association studies using novel polymorphisms in BACE1 and BACE2.

1 reference

12 December 2020

Functional implications of genetic variation in non-coding DNA for disease susceptibility and gene regulation

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12 December 2020

Coordinated Expression of β-Amyloid Precursor Protein and the Putative β-Secretase BACE and α-Secretase ADAM10 in Mouse and Human Brain

1 reference

12 December 2020

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

1 reference

12 December 2020

Leaky scanning and reinitiation regulate BACE1 gene expression

1 reference

12 December 2020

Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1.

1 reference

12 December 2020

Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1

1 reference

12 December 2020

Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

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12 December 2020

Single-nucleotide promoter polymorphism alters transcription of neuronal nitric oxide synthase exon 1c in infantile hypertrophic pyloric stenosis

1 reference

12 December 2020

The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1.

1 reference

12 December 2020

Differential utilization of upstream AUGs in the beta-secretase mRNA suggests that a shunting mechanism regulates translation

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12 December 2020

Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression

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12 December 2020

Translational regulation of BACE-1 expression in neuronal and non-neuronal cells

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12 December 2020

Alzheimer's disease and oxygen radicals: new insights

1 reference

12 December 2020

Specific BACE1 genotypes provide additional risk for late‐onset alzheimer disease in APOE ε4 carriers

1 reference

12 December 2020

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

12 December 2020

Oxidative stress potentiates BACE1 gene expression and Abeta generation

1 reference

12 December 2020

Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

1 reference

12 December 2020

Distinct transcriptional regulation and function of the human BACE2 and BACE1 genes

1 reference

12 December 2020

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

1 reference

12 December 2020

The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1.

1 reference

12 December 2020

BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome

1 reference

12 December 2020

Alzheimer's disease: genes, proteins, and therapy

1 reference

12 December 2020

Polymorphism in the BACE gene influences the risk for Alzheimer's disease

1 reference

12 December 2020

Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase

1 reference

12 December 2020

Dimerization of beta-site beta-amyloid precursor protein-cleaving enzyme

1 reference

12 December 2020

Mutations in the open reading frame of the beta-site APP cleaving enzyme (BACE) locus are not a common cause of Alzheimer's disease.

1 reference

12 December 2020

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

1 reference

12 December 2020

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

1 reference

12 December 2020

Control of APP processing and Abeta generation level by BACE1 enzymatic activity and transcription

1 reference

12 December 2020

BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

1 reference

12 December 2020

Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

1 reference

12 December 2020

Presenilin-1 mutations in Alzheimer's disease.

1 reference

12 December 2020

Genetic studies of A2M and BACE1 genes in Chinese Han Alzheimer's disease patients

1 reference

12 December 2020

Involvement of beta-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity.

1 reference

12 December 2020

Amyloid beta secretase gene (BACE) is neither mutated in nor associated with early-onset Alzheimer's disease

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12 December 2020

The genetics of Alzheimer disease: current status and future prospects

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12 December 2020

Expression of the Alzheimer protease BACE1 is suppressed via its 5'-untranslated region

1 reference

12 December 2020

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

1 reference

12 December 2020

10.1007/S12031-010-9381-6

Identifiers

DOI

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14 September 2017

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