(Q39711118)

14 September 2017

Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting (English)

1 reference

14 September 2017

0 references

0 references

24

Kimberly Stegmaier

1 reference

14 September 2017

Coyin Oh

20

0 references

Robin M Meyers

Robin M Meyers

2

0 references

Aviad Tsherniak

Aviad Tsherniak

29

0 references

Francisca Vazquez

Francisca Vazquez

4

0 references

Gavin Ha

Gavin Ha

8

0 references

Charles W Roberts

Charles W Roberts

25

0 references

Matthew Meyerson

Matthew Meyerson

27

0 references

Levi A Garraway

23

Levi A Garraway

1 reference

14 September 2017

26

Todd R Golub

1 reference

14 September 2017

30

William C Hahn

1 reference

14 September 2017

28

David E Root

1 reference

14 September 2017

22

Glenn S Cowley

1 reference

14 September 2017

3

Barbara A Weir

1 reference

14 September 2017

19

Andrew D Cherniack

1 reference

14 September 2017

Andrew J Aguirre

1

1 reference

14 September 2017

Cheng-Zhong Zhang

5

1 reference

14 September 2017

Uri Ben-David

6

1 reference

14 September 2017

April Cook

7

1 reference

14 September 2017

William F Harrington

9

1 reference

14 September 2017

Mihir B Doshi

10

1 reference

14 September 2017

Maria Kost-Alimova

11

1 reference

14 September 2017

Stanley Gill

12

1 reference

14 September 2017

Han Xu

13

1 reference

14 September 2017

Levi D Ali

14

1 reference

14 September 2017

Guozhi Jiang

15

1 reference

14 September 2017

Sasha Pantel

16

1 reference

14 September 2017

Yenarae Lee

17

1 reference

14 September 2017

Amy Goodale

18

1 reference

14 September 2017

Gregory Kryukov

21

1 reference

14 September 2017

3 June 2016

1 reference

14 September 2017

1 reference

14 September 2017

6

1 reference

14 September 2017

914-929

1 reference

14 September 2017

8

1 reference

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Identification and characterization of essential genes in the human genome.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Multiparametric Cell Cycle Analysis Using the Operetta High-Content Imager and Harmony Software with PhenoLOGIC

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

High-throughput functional genomics using CRISPR-Cas9.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Rapid modelling of cooperating genetic events in cancer through somatic genome editing

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

CRISPR-Cas9 knockin mice for genome editing and cancer modeling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

CRISPR-mediated direct mutation of cancer genes in the mouse liver

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Improved vectors and genome-wide libraries for CRISPR screening

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Development and applications of CRISPR-Cas9 for genome engineering

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

CRISPR-Cas systems for editing, regulating and targeting genomes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Genome-scale CRISPR-Cas9 knockout screening in human cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Genetic screens in human cells using the CRISPR-Cas9 system

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

CRISPR RNA-guided activation of endogenous human genes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Optical control of mammalian endogenous transcription and epigenetic states

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

RNA-programmed genome editing in human cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Highly recurrent TERT promoter mutations in human melanoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

RNA-guided human genome engineering via Cas9

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Multiplex genome engineering using CRISPR/Cas systems

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

TALENs: a widely applicable technology for targeted genome editing

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Absolute quantification of somatic DNA alterations in human cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Strategies to improve radiotherapy with targeted drugs

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Genome editing with engineered zinc finger nucleases

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

The landscape of somatic copy-number alteration across human cancers

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Fast and accurate short read alignment with Burrows-Wheeler transform

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

Timeline: Chemotherapy and the war on cancer.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972686

10.1158/2159-8290.CD-16-0154

15 June 2018

Identifiers

DOI

1 reference

14 September 2017

1 reference

14 September 2017

1 reference