(Q39734014)

14 September 2017

Cross talk between stimulated NF-kappaB and the tumor suppressor p53. (English)

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14 September 2017

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14

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14 September 2017

G Schneider

1

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14 September 2017

A Henrich

2

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14 September 2017

G Greiner

3

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14 September 2017

V Wolf

4

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14 September 2017

A Lovas

5

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14 September 2017

M Wieczorek

6

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14 September 2017

T Wagner

7

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14 September 2017

S Reichardt

8

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14 September 2017

A von Werder

9

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14 September 2017

R M Schmid

10

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14 September 2017

F Weih

11

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14 September 2017

T Heinzel

12

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14 September 2017

D Saur

13

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14 September 2017

language of work or name

English

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publication date

1 March 2010

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14 September 2017

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14 September 2017

29

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14 September 2017

2795-2806

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14 September 2017

19

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https://scigraph.springernature.com/pub.10.1038/onc.2010.46

14 September 2017

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cites work

P53 family: at the crossroads in cancer therapy

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https://api.crossref.org/works/10.1038%2FONC.2010.46

Cell cycle regulation of NF-kappa b-binding activity in cells from human glioblastomas.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.46

High-frequency developmental abnormalities in p53-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Signaling from p53 to NF-kappa B determines the chemotherapy responsiveness of neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Cancer cells suppress p53 in adjacent fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Clinical trial of valproic acid and all-trans retinoic acid in patients with poor-risk acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

The common biology of cancer and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.46

Inhibitors of NF-kappaB signaling: 785 and counting

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.46

p53 accumulates but is functionally impaired when DNA synthesis is blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

The multiple facets of the intra-S checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Caffeic acid phenethyl ester inhibits osteoclastogenesis by suppressing NF kappaB and downregulating NFATc1 and c-Fos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

21 January 2018

The Hallmarks of Cancer

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https://api.crossref.org/works/10.1038%2FONC.2010.46

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Stalled replication induces p53 accumulation through distinct mechanisms from DNA damage checkpoint pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Signals from within: the DNA-damage-induced NF-kappaB response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Nuclear factor-kappaB in cancer development and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Expression of the Bcl-3 proto-oncogene suppresses p53 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

p53 transcriptional activation domain: a molecular chameleon?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Activated p53 induces NF-kappaB DNA binding but suppresses its transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Nuclear export is essential for the tumor-promoting activity of survivin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

HDAC2: a critical factor in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Acetylation of Stat1 modulates NF-kappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Histone deacetylase inhibitors and hydroxyurea modulate the cell cycle and cooperatively induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

A phosphorylation-acetylation switch regulates STAT1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Involvement of tumor suppressor protein p53 and p38 MAPK in caffeic acid phenethyl ester-induced apoptosis of C6 glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Replicational stress selects for p53 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Transcription-independent pro-apoptotic functions of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Stabilization of p53 and transactivation of its target genes in response to replication blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

The nuclear factor-kappaB and p53 pathways function independently in primary cells and transformed fibroblasts responding to genotoxic damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Targeting the Fas/Fas ligand pathway in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Integrating cell-signalling pathways with NF-kappaB and IKK function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Autoregulatory feedback loops terminating the NF-kappaB response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Response of tumour cells to hypoxia: role of p53 and NFkB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Role of NF-κB in p53-mediated programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Inhibition of p53 protects liver tissue against endotoxin-induced apoptotic and necrotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

IkappaB kinase complexes: gateways to NF-kappaB activation and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

IKKalpha controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Regulation of p53 tumour suppressor target gene expression by the p52 NF-kappaB subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Tumor-derived p53 mutants induce NF-kappaB2 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

A Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Shaping genetic alterations in human cancer: the p53 mutation paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Acetylation of non-histone proteins modulates cellular signalling at multiple levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

NFkappaB pathway: a good signaling paradigm and therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Protein-protein interaction networks: how can a hub protein bind so many different partners?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

p53 in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

CREB-binding protein is a nuclear integrator of nuclear factor-kappaB and p53 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Restoration of p53 to limit tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Transcriptional cross talk between NF-kappaB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Induction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Riboflavin kinase couples TNF receptor 1 to NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

ATM-dependent nuclear accumulation of IKK-alpha plays an important role in the regulation of p73-mediated apoptosis in response to cisplatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Cell fate decision mediated by p53 pulses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Hydroxyurea for treatment of unresectable meningiomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Signaling from p53 to NF-kappaB determines the chemotherapy responsiveness of neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Mutant p53: from guardian to fallen angel?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Immortalized fibroblasts from NF-kappaB RelA knockout mice show phenotypic heterogeneity and maintain increased sensitivity to tumor necrosis factor alpha after transformation by v-Ras

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

IFN-gamma protects cerulein-induced acute pancreatitis by repressing NF-kappa B activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Identification of a novel pro-apopotic function of NF-kappaB in the DNA damage response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

Diversity and regulation in the NF-kappaB system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.46

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.46

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14 September 2017

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