(Q39798829)

English

The Ah locus: genetic regulation of the metabolism of carcinogens, drugs, and other environmental chemicals by cytochrome P-450-mediated monooxygenases.

scientific article published on January 1979

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scholarly article

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Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

The Ah locus: genetic regulation of the metabolism of carcinogens, drugs, and other environmental chemicals by cytochrome P-450-mediated monooxygenases. (English)

1 reference

Europe PubMed Central

14 September 2017

author name string

Nebert DW

1

1 reference

Europe PubMed Central

14 September 2017

Jensen NM

2

1 reference

Europe PubMed Central

14 September 2017

language of work or name

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based on heuristic

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publication date

1 January 1979

1 reference

Europe PubMed Central

14 September 2017

CRC critical reviews in biochemistry

1 reference

Europe PubMed Central

14 September 2017

6

1 reference

Europe PubMed Central

14 September 2017

401-437

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Europe PubMed Central

14 September 2017

4

1 reference

Europe PubMed Central

14 September 2017

Arene oxides: a new aspect of drug metabolism.

1 reference

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21 January 2018

Chemical carcinogenesis

1 reference

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21 January 2018

Enzymic reduction of aromatic hydrocarbon epoxides by the microsomal fraction of rat liver.

1 reference

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21 January 2018

Evidence for the involvement of cytochrome P-450 in reduction of benzo(a)pyrene 4,5-oxide by rat liver microsomes

1 reference

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21 January 2018

Genetic expression of aryl hydrocarbon hydroxylase activity in the mouse

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21 January 2018

Genetic aspects of toxicity during development

1 reference

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21 January 2018

Genetic association of increases in naphthalene, acetanilide, and biphenyl hydroxylations with inducible aryl hydrocarbon hydroxylase in mice

1 reference

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21 January 2018

The stimulation of hydroxylation by carcinogenic and non-carcinogenic compounds.

1 reference

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21 January 2018

Influence of inducers and inhibitors on the hydroxylation pattern of N-hexane in rat liver microsomes.

1 reference

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21 January 2018

Effects of inducers and epoxide hydrase on the metabolism of benzo(a)pyrene by liver microsomes and a reconstituted system: analysis by high pressure liquid chromatography

1 reference

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21 January 2018

Arene oxides and the NIH shift: the metabolism, toxicity and carcinogenicity of aromatic compounds.

1 reference

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21 January 2018

A rapid assay for epoxide hydratase activity with benzo (a)pyrene 4,5-(K-region)-oxide as substrate.

1 reference

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21 January 2018

Genetic expression of aryl hydrocarbon hydroxylase induction. VI. Control of other aromatic hydrocarbon-inducible mono-oxygenase activities at or near the same genetic locus.

1 reference

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21 January 2018

Phenolic benzo(a)pyrene metabolites are mutagens

1 reference

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21 January 2018

Effects of microsomal enzyme inducers in vivo and inhibitors in vitro on the covalent binding of benzo[a]pyrene metabolites to DNA catalyzed by liver microsomes from genetically responsive and nonresponsive mice

1 reference

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21 January 2018

Benzo[a]pyrene 7,8-dihydrodiol is more carcinogenic than benzo[a]pyrene in newborn mice

1 reference

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21 January 2018

Carcinogenicity of benzo[a]pyrene 4,5-, 7,8-, and 9,10-oxides on mouse skin

1 reference

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21 January 2018

Identification of mutagenic metabolites of benzo(a)pyrene in mammalian cells

1 reference

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21 January 2018

Mutagenicity of non-K-region diols and diol-epoxides of benz(a)anthracene and benzo(a)pyrene in S. typhimurium TA 100

1 reference

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21 January 2018

Birth defects and aplastic anemia: differences in polycyclic hydrocarbon toxicity associated with the Ah locus.

1 reference

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21 January 2018

The genetic basis of susceptibility to leukemia induction in mice by 3-methylcholanthrene applied percutaneously

1 reference

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21 January 2018

Mutagenic and cytotoxic activity of benzol[a]pyrene 4,5-, 7,8-, and 9,10-oxides and the six corresponding phenols

1 reference

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21 January 2018

beta-Glucuronidase catalyzed hydrolysis of benzo(a)pyrene-3-glucuronide and binding to DNA

1 reference

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21 January 2018

Genetic control of glucuronidase induction in mice

1 reference

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21 January 2018

Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test

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21 January 2018

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals

1 reference

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21 January 2018

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion

1 reference

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21 January 2018

Conversion of naphthalene to trans-naphthalene dihydrodiol: evidence for the presence of a coupled aryl monooxygenase-epoxide hydrase system in hepatic microsomes.

1 reference

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21 January 2018

Acetaminophen-induced hepatic necrosis. V. Correlation of hepatic necrosis, covalent binding and glutathione depletion in hamsters.

1 reference

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21 January 2018

Lens cataract formation and reversible alteration in crystallin synthesis in cultured lenses

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21 January 2018

-Crystallin. The isolation and characterization of distinct macromolecular fractions.

1 reference

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21 January 2018

Absence of low-molecular-weight alpha crystallin in nuclear region of old human lenses

1 reference

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21 January 2018

THE NATURE OF THE OCULAR LESIONS PRODUCED EXPERIMENTALLY BY NAPHTHALENE.

1 reference

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21 January 2018

The metabolism of naphthalene and its toxic effect on the eye.

1 reference

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21 January 2018

Ah locus: genetic differences in susceptibility to cataracts induced by acetaminophen

1 reference

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21 January 2018

Aryl hydrocarbon hydroxylase inducibility and bronchogenic carcinoma.

1 reference

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21 January 2018

Assignment of a locus required for flavoprotein-linked monooxygenase expression to human chromosome 2

1 reference

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21 January 2018

Independent regulation of two types of aryl hydrocarbon (benzo(a)pyrene) hydroxylase in mammalian cells

1 reference

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21 January 2018

The molecular genetics of mammalian glucuronidase

1 reference

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21 January 2018

Relationships between aryl hydrocarbon hydroxylase inducibility and sensitivity to chemically induced subcutaneous sarcomas in various strains of mice.

1 reference

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21 January 2018

Evidence of a genetic relationship between susceptibility to 3-methyl-cholanthrene-induced subcutaneous tumors and inducibility of aryl hydrocarbon hydroxylase.

1 reference

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21 January 2018

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

1 reference

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21 January 2018

Identifiers

10.3109/10409237909105427

1 reference

Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

14 September 2017

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