(Q39810065)

14 September 2017

p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYC. (English)

1 reference

14 September 2017

R Shalgi

2

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Mikkel Klausen

object named as

M Klausen

6

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Eleonora Leucci

object named as

E Leucci

4

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author name string

N R Christoffersen

1

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14 September 2017

L B Frankel

3

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14 September 2017

M Lees

5

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14 September 2017

Y Pilpel

7

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14 September 2017

F C Nielsen

8

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14 September 2017

M Oren

9

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14 September 2017

A H Lund

10

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14 September 2017

21 August 2009

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Cell Death & Differentiation

14 September 2017

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14 September 2017

17

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14 September 2017

236-245

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14 September 2017

2

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https://scigraph.springernature.com/pub.10.1038/cdd.2009.109

14 September 2017

0 references

cites work

A DNA damage checkpoint response in telomere-initiated senescence

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

DNA damage foci at dysfunctional telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

A negative feedback signaling network underlies oncogene-induced senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Breaking news: high-speed race ends in arrest--how oncogenes induce senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Many roads lead to oncogene-induced senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Oncogene-induced cell senescence--halting on the road to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

OncomiRs: the discovery and progress of microRNAs in cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

A microRNA component of the p53 tumour suppressor network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Senescence of human fibroblasts induced by oncogenic Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

rVista for comparative sequence-based discovery of functional transcription factor binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

DAVID: Database for Annotation, Visualization, and Integrated Discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Transcription factor and microRNA motif discovery: the Amadeus platform and a compendium of metazoan target sets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

The quest for the 1p36 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Silencing of microRNAs in vivo with 'antagomirs'

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Tiny actors, great roles: microRNAs in p53's service.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

The MYCN oncogene is a direct target of miR-34a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

Use of bifunctional cross-linking reagents in mapping genomic distribution of chromatin remodeling complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

p19ARF links the tumour suppressor p53 to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

MYCtranslocation-negative classical Burkitt lymphoma cases: an alternative pathogenetic mechanism involving miRNA deregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.109

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7 January 2021

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Identifiers

DOI

10.1038/CDD.2009.109

1 reference

release_2cfss4e23jbz3niwze4nxmy4pu

14 September 2017

0 references

1 reference