(Q39815562)

14 September 2017

Dephosphorylation and inactivation of Akt/PKB is counteracted by protein kinase CK2 in HEK 293T cells (English)

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14 September 2017

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14 September 2017

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14 September 2017

4

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14 September 2017

Francesca Brustolon

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PubMed ID

19662498

14 September 2017

language of work or name

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8 August 2009

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Cellular and Molecular Life Sciences

14 September 2017

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14 September 2017

66

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14 September 2017

3363-3373

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14 September 2017

20

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https://scigraph.springernature.com/pub.10.1007/s00018-009-0108-1

14 September 2017

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cites work

Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2.

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Crossref

https://api.crossref.org/works/10.1007%2FS00018-009-0108-1

Modulation of Akt kinase activity by binding to Hsp90

21 January 2018

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12 December 2020

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

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12 December 2020

Pharmacological inhibition of protein kinase CK2 reverts the multidrug resistance phenotype of a CEM cell line characterized by high CK2 level.

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12 December 2020

Protein kinase CK2: a challenge to canons

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12 December 2020

The protooncogene TCL1 is an Akt kinase coactivator

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12 December 2020

Protein kinase CK2 subunits are positive regulators of AKT kinase

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12 December 2020

Targeting CK2 for cancer therapy

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12 December 2020

Protein kinase CK2 impairs spatial memory formation through differential cross talk with PI-3 kinase signaling: activation of Akt and inactivation of SGK1.

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12 December 2020

Okadaic acid: a new probe for the study of cellular regulation

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12 December 2020

The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation

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12 December 2020

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

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12 December 2020

Recent advances in the protein kinase B signaling pathway

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12 December 2020

Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

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12 December 2020

The 90-kDa heat shock protein, HSP90, binds and protects casein kinase II from self-aggregation and enhances its kinase activity.

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12 December 2020

Protein kinase CK2 as a druggable target

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12 December 2020

Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function

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12 December 2020

Specificity and mechanism of action of some commonly used protein kinase inhibitors

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12 December 2020

Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane

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12 December 2020

Tcl1 enhances Akt kinase activity and mediates its nuclear translocation

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12 December 2020

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

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12 December 2020

Protein kinase CK2--a key suppressor of apoptosis

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12 December 2020

CK2: a protein kinase in need of control.

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12 December 2020

Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').

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12 December 2020

Direct identification of PTEN phosphorylation sites

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12 December 2020

Natural Product Origins of Hsp90 Inhibitors

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12 December 2020

Discrimination between the activity of protein kinase CK2 holoenzyme and its catalytic subunits.

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12 December 2020

AKT/PKB signaling: navigating downstream

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12 December 2020

PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival

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12 December 2020

Akt signaling and cancer: surviving but not moving on.

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12 December 2020

CK2 controls multiple protein kinases by phosphorylating a kinase-targeting molecular chaperone, Cdc37.

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12 December 2020

Activation of protein kinase B (Akt/RAC-protein kinase) by cellular stress and its association with heat shock protein Hsp27.

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12 December 2020

AKT crystal structure and AKT-specific inhibitors

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12 December 2020

Protein kinase CK2 as regulator of cell survival: implications for cancer therapy

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12 December 2020

Protein kinase CK2 phosphorylates and upregulates Akt/PKB.

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12 December 2020

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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12 December 2020

Protein kinase B: signalling roles and therapeutic targeting

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12 December 2020

One-thousand-and-one substrates of protein kinase CK2?

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12 December 2020

Protein kinase B alpha/Akt1 regulates placental development and fetal growth

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12 December 2020

Protein kinase CK2: a newcomer in the 'druggable kinome'.

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12 December 2020

Protein kinase B/Akt at a glance

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12 December 2020

10.1007/S00018-009-0108-1

Identifiers

DOI

1 reference

release_xfd4sj32mvdi3cnztiq524n6hu

14 September 2017

0 references

PubMed ID

19662498

1 reference

PubMed ID

19662498