(Q39829234)

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Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19578044%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19578044%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

apoptotic process

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1

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1 February 2020

3

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1 February 2020

author name string

Elif Damla Arisan

2

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1 February 2020

Maria C Shoshan

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19578044%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Huveyda Basaga

5

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1 February 2020

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3 July 2009

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1 February 2020

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Europe PubMed Central

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1 February 2020

30

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1 February 2020

9

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1 February 2020

1517-1527

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1 February 2020

Recent advances in targeting regulators of apoptosis in cancer cells for therapeutic gain

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Bcl-2 attenuates anticancer agents-induced apoptosis by sustained activation of Akt/protein kinase B in U937 cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Bcl-2 is a key regulator for the retinoic acid-induced apoptotic cell death in neuroblastoma

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Bcl-2 is the target of a UV-inducible apoptosis switch and a node for UV signaling

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Diagnosing and exploiting cancer's addiction to blocks in apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Methylglyoxal induces apoptosis through oxidative stress-mediated activation of p38 mitogen-activated protein kinase in rat Schwann cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

BCL-2 is involved in preventing oxidant-induced cell death and in decreasing oxygen radical production.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

p53-Dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Apoptosis by cisplatin requires p53 mediated p38alpha MAPK activation through ROS generation.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Evidence that p53-mediated cell-cycle-arrest inhibits chemotherapeutic treatment of ovarian carcinomas

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

p53 has a direct apoptogenic role at the mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Mitochondrially targeted p53 has tumor suppressor activities in vivo

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

A novel high-through-put assay for screening of pro-apoptotic drugs

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Cellular toxicity of hydrazine in primary rat hepatocytes

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Application of lipid peroxidation and protein oxidation biomarkers for oxidative damage in mammalian cells. A comparison with two fluorescent probes.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Proapoptotic BAX and BAK control multiple initiator caspases

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Activation of Bak, Bax, and BH3-only proteins in the apoptotic response to doxorubicin.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Sensitization for anticancer drug-induced apoptosis by betulinic Acid

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Differential roles of hydrogen peroxide and hydroxyl radical in cisplatin-induced cell death in renal proximal tubular epithelial cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

DNA damage induces two distinct modes of cell death in ovarian carcinomas

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Cisplatin induces endoplasmic reticulum stress and nucleus-independent apoptotic signaling

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Bax and Bak independently promote cytochrome C release from mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

A role for mitochondrial Bak in apoptotic response to anticancer drugs

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Cisplatin induces the proapoptotic conformation of Bak in a deltaMEKK1-dependent manner

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Two distinct steps of Bak regulation during apoptotic stress signaling: different roles of MEKK1 and JNK1.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Activation of the mitochondrial death pathway is commonly mediated by a preferential engagement of Bak.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

PUMA, a novel proapoptotic gene, is induced by p53

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

The BH3-only protein, PUMA, is involved in oxaliplatin-induced apoptosis in colon cancer cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

Acute apoptosis by cisplatin requires induction of reactive oxygen species but is not associated with damage to nuclear DNA

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP165

21 January 2018

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