(Q39954065)

15 September 2017

Diminishing returns epistasis among beneficial mutations decelerates adaptation (English)

1 reference

15 September 2017

1 reference

Hsin-Hung Chou

1

1 reference

15 September 2017

Hsuan-Chao Chiu

2

1 reference

15 September 2017

Nigel F Delaney

3

1 reference

15 September 2017

Daniel Segrè

4

1 reference

15 September 2017

Christopher J Marx

5

1 reference

15 September 2017

language of work or name

English

0 references

publication date

1 June 2011

1 reference

15 September 2017

1 reference

15 September 2017

332

1 reference

15 September 2017

1190-1192

1 reference

15 September 2017

6034

1 reference

The dynamics of adaptation on correlated fitness landscapes

15 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

Genome evolution and adaptation in a long-term experiment with Escherichia coli

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

Fast growth increases the selective advantage of a mutation arising recurrently during evolution under metal limitation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

Impact of individual mutations on increased fitness in adaptively evolved strains of Escherichia coli

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

Darwinian evolution can follow only very few mutational paths to fitter proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

Evolution of hormone-receptor complexity by molecular exploitation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

The biochemical architecture of an ancient adaptive landscape

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

Optimality and evolutionary tuning of the expression level of a protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

The contribution of epistasis to the architecture of fitness in an RNA virus

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

Formaldehyde-detoxifying role of the tetrahydromethanopterin-linked pathway in Methylobacterium extorquens AM1.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

Microbial genetics: Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

Bacterial growth inhibition by overproduction of protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

C1 transfer enzymes and coenzymes linking methylotrophic bacteria and methanogenic Archaea.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

Distributions of epistasis in microbes fit predictions from a fitness landscape model.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

Modular epistasis in yeast metabolism.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244271

Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugged fitness landscape

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1203799

Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1203799

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1203799

1 reference

15 September 2017

1 reference

15 September 2017

1 reference