(Q39956832)

15 September 2017

Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects (English)

1 reference

15 September 2017

10

1 reference

15 September 2017

M Hall

7

0 references

author name string

A D Michel

1

1 reference

15 September 2017

W C Clay

2

1 reference

15 September 2017

S W Ng

3

1 reference

15 September 2017

S Roman

4

1 reference

15 September 2017

K Thompson

5

1 reference

15 September 2017

J P Condreay

6

1 reference

15 September 2017

J Holbrook

8

1 reference

15 September 2017

D Livermore

9

1 reference

15 September 2017

language of work or name

English

0 references

publication date

28 July 2008

1 reference

British Journal of Pharmacology

15 September 2017

1 reference

15 September 2017

155

1 reference

15 September 2017

738-751

1 reference

15 September 2017

5

1 reference

Negative and positive allosteric modulators of the P2X(7) receptor

15 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Cloning and pharmacological characterization of the guinea pig P2X7 receptor orthologue

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Agonist potency at P2X7 receptors is modulated by structurally diverse lipids

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Discovery of P2X7 receptor-selective antagonists offers new insights into P2X7 receptor function and indicates a role in chronic pain states

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Characterization of a selective and potent antagonist of human P2X(7) receptors, AZ11645373.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Species and response dependent differences in the effects of MAPK inhibitors on P2X(7) receptor function

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

The P2X7 receptor: a key player in IL-1 processing and release

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Decavanadate, a P2X receptor antagonist, and its use to study ligand interactions with P2X7 receptors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

A His-155 to Tyr polymorphism confers gain-of-function to the human P2X7 receptor of human leukemic lymphocytes.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Agonists and antagonists acting at P2X7 receptor.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Molecular properties of ATP-gated P2X receptor ion channels

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Recombinant baculoviruses used to study estrogen receptor function in human osteosarcoma cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Molecular physiology of P2X receptors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Complexities of measuring antagonist potency at P2X(7) receptor orthologs.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Effects of antagonists at the human recombinant P2X7 receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

The isoquinoline derivative KN-62 a potent antagonist of the P2Z-receptor of human lymphocytes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Ionic effects on human recombinant P2X7 receptor function

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Direct labelling of the human P2X7 receptor and identification of positive and negative cooperativity of binding

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Isoquinolines as antagonists of the P2X7 nucleotide receptor: high selectivity for the human versus rat receptor homologues.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Guide to Receptors and Channels (GRAC), 3rd edition

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Brilliant blue G selectively blocks ATP-gated rat P2X(7) receptors.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Integration of PCR fragments at any specific site within cloning vectors without the use of restriction enzymes and DNA ligase

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18660826

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Amino Acid Residues in the P2X7 Receptor that Mediate Differential Sensitivity to ATP and BzATP

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18660826

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/BJP.2008.306

1 reference

15 September 2017

1 reference

15 September 2017

1 reference