(Q39969437)

16 September 2017

title

Tranilast, an antifibrogenic agent, ameliorates a dietary rat model of nonalcoholic steatohepatitis (English)

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16 September 2017

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Masafumi Uno

1

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16 September 2017

Seiichiro Kurita

2

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16 September 2017

Hirofumi Misu

3

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16 September 2017

Hitoshi Ando

4

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16 September 2017

Tsuguhito Ota

5

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16 September 2017

Naoto Matsuzawa-Nagata

6

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16 September 2017

Yuki Kita

7

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16 September 2017

Satoko Nabemoto

8

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16 September 2017

Hiroshi Akahori

9

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16 September 2017

Yoh Zen

10

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16 September 2017

Yasuni Nakanuma

11

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16 September 2017

Shuichi Kaneko

12

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16 September 2017

Toshinari Takamura

13

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16 September 2017

language of work or name

English

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publication date

1 July 2008

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16 September 2017

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16 September 2017

volume

48

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16 September 2017

issue

1

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16 September 2017

page(s)

109-118

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Lipopolysaccharides in liver injury: molecular mechanisms of Kupffer cell activation

16 September 2017

cites work

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Role of Kupffer cells in the pathogenesis of liver disease

21 January 2018

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Nonalcoholic steatohepatitis

21 January 2018

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7 January 2021

Nonalcoholic fatty liver disease

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7 January 2021

Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome

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7 January 2021

Nonalcoholic fatty liver disease: a feature of the metabolic syndrome

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7 January 2021

Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis

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7 January 2021

Inhibitory action of tranilast, an anti-allergic drug, on the release of cytokines and PGE2 from human monocytes-macrophages

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7 January 2021

Tranilast attenuates vascular hypertrophy, matrix accumulation and growth factor overexpression in experimental diabetes

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7 January 2021

Inhibitory effect of tranilast on activation and transforming growth factor beta 1 expression in cultured rat stellate cells

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7 January 2021

Inhibition of PDGF- and TGF-beta 1-induced collagen synthesis, migration and proliferation by tranilast in vascular smooth muscle cells from spontaneously hypertensive rats

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7 January 2021

Therapeutic strategies against TGF-beta signaling pathway in hepatic fibrosis

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7 January 2021

Regulation of extracellular matrix synthesis by transforming growth factor beta 1 in human fat-storing cells

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7 January 2021

In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: a potential new therapy for hepatic fibrosis

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7 January 2021

Adenoviral expression of a transforming growth factor-beta1 antisense mRNA is effective in preventing liver fibrosis in bile-duct ligated rats

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7 January 2021

Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat.

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7 January 2021

Inhibition of transforming growth factor beta prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosamine-treated rats

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7 January 2021

Increased expression of connective tissue growth factor in fibrotic human liver and in activated hepatic stellate cells.

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7 January 2021

Treatment of keloid and hypertrophic scars by iontophoretic transdermal delivery of tranilast

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7 January 2021

Tranilast, a selective inhibitor of collagen synthesis in human skin fibroblasts

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7 January 2021

Tranilast prevents the progression of experimental diabetic nephropathy through suppression of enhanced extracellular matrix gene expression.

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7 January 2021

Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain

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7 January 2021

Genes for systemic vascular complications are differentially expressed in the livers of type 2 diabetic patients.

1 reference

7 January 2021

Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet.

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7 January 2021

Tranilast inhibits transplant-associated coronary arteriosclerosis in a murine model of cardiac transplantation

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7 January 2021

Tranilast inhibits cardiac allograft vasculopathy in association with p21(Waf1/Cip1) expression on neointimal cells in murine cardiac transplantation model

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7 January 2021

Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets

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7 January 2021

Roles of TGF-beta in hepatic fibrosis

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7 January 2021

Metformin prevents alcohol-induced liver injury in the mouse: Critical role of plasminogen activator inhibitor-1

1 reference

7 January 2021

A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis

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7 January 2021

Inhibition of PPAR-α activity in mice with cardiac-restricted expression of tumor necrosis factor: potential role of TGF-β/Smad3

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7 January 2021

Towards a molecular understanding of adaptive thermogenesis

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7 January 2021

Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice

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7 January 2021

Identifiers

DOI

10.1002/HEP.22338

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16 September 2017

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