(Q40023794)

16 September 2017

A novel p53 rescue compound induces p53-dependent growth arrest and sensitises glioma cells to Apo2L/TRAIL-induced apoptosis (English)

1 reference

16 September 2017

L Weinmann

1

1 reference

16 September 2017

J Wischhusen

2

1 reference

16 September 2017

M J Demma

3

1 reference

16 September 2017

U Naumann

4

1 reference

16 September 2017

P Roth

5

1 reference

16 September 2017

B Dasmahapatra

6

1 reference

16 September 2017

M Weller

7

1 reference

16 September 2017

language of work or name

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18 January 2008

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Cell Death & Differentiation

16 September 2017

1 reference

16 September 2017

15

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16 September 2017

718-729

1 reference

16 September 2017

4

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4402301

16 September 2017

0 references

cites work

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

APO2 ligand: a novel lethal weapon against malignant glioma?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

p53 and its family members -- reporter genes may not see the difference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Glioma cell sensitivity to topotecan: the role of p53 and topotecan-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells. Induction and modulation of sensitivity by cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Restoration of p53 function leads to tumour regression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Modeling the therapeutic efficacy of p53 restoration in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Characterization of the p53-rescue drug CP-31398 in vitro and in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

TAp73/Delta Np73 influences apoptotic response, chemosensitivity and prognosis in hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Parc: a cytoplasmic anchor for p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Predicting response to cancer chemotherapy: the role of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Signal transduction and cellular radiation responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

Pharmacological rescue of mutant p53 conformation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

7 January 2021

CP-31398 restores DNA-binding activity to mutant p53 in vitro but does not affect p53 homologs p63 and p73

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

7 January 2021

Criteria for analyzing interactions between biologically active agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

7 January 2021

The p53-stabilizing compound CP-31398 enhances ultraviolet-B-induced apoptosis in a human melanoma cell line MMRU

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

7 January 2021

Local Fas/APO-1 (CD95) ligand-mediated tumor cell killing in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402301

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402301

1 reference

Dimensions Publication ID

16 September 2017

0 references

1 reference