(Q40081558)

17 September 2017

Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers (English)

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17 September 2017

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Ina Hubatsch

1

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17 September 2017

Eva G E Ragnarsson

series ordinal

2

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17 September 2017

Per Artursson

series ordinal

3

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17 September 2017

1 January 2007

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17 September 2017

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17 September 2017

2

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17 September 2017

2111-2119

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17 September 2017

9

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https://scigraph.springernature.com/pub.10.1038/nprot.2007.303

17 September 2017

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cites work

Caco-2 monolayers in experimental and theoretical predictions of drug transport

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

Experimental and computational screening models for the prediction of intestinal drug absorption

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

Orally active antiviral tripeptide glycyl-prolyl-glycinamide is activated by CD26 (dipeptidyl peptidase IV) before transport across the intestinal epithelium

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

Impact of extracellular protein binding on passive and active drug transport across Caco-2 cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

pH-dependent bidirectional transport of weakly basic drugs across Caco-2 monolayers: implications for drug-drug interactions.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

pH-Dependent passive and active transport of acidic drugs across Caco-2 cell monolayers.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

pH-profile and regional transit times of the normal gut measured by a radiotelemetry device

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

Optimized conditions for prediction of intestinal drug permeability using Caco-2 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

New and better protocols for a short-term Caco-2 cell culture system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

Caco-2 permeability of weakly basic drugs predicted with the double-sink PAMPA pKa(flux) method.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

A new method for drug transport studies on pig nasal mucosa using a horizontal Ussing chamber

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

Absorption classification of oral drugs based on molecular surface properties

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

Correlation of in vitro cytotoxicity with paracellular permeability in Caco-2 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

The steady-state Michaelis-Menten analysis of P-glycoprotein mediated transport through a confluent cell monolayer cannot predict the correct Michaelis constant Km.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

Quantification and characterization of P-glycoprotein-substrate interactions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

Decrease in intracellular concentration causes the shift in Km value of efflux pump substrates.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

A global drug inhibition pattern for the human ATP-binding cassette transporter breast cancer resistance protein (ABCG2).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

The oligopeptide transporter (Pept-1) in human intestine: biology and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

Predominant contribution of organic anion transporting polypeptide OATP-B (OATP2B1) to apical uptake of estrone-3-sulfate by human intestinal Caco-2 cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.303

31 March 2020

Identifiers

DOI

10.1038/NPROT.2007.303

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Dimensions Publication ID

17 September 2017

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