(Q401536)

Protein kinase-like domain superfamily

1 reference

SH2 domain superfamily

1 reference

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

SH2 domain, protein family

1 reference

Tyrosine-protein kinase Blk, SH2 domain, protein family

1 reference

SH3 domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

1 reference

8 April 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

1 reference

8 April 2019

protein kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

1 reference

8 April 2019

kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

1 reference

8 April 2019

protein binding

4 references

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

8 April 2019

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

8 April 2019

A quantitative protein interaction network for the ErbB receptors using protein microarrays

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

8 April 2019

The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

protein tyrosine kinase activity

Molecular cloning and chromosomal localization of the human homologue of a B-lymphocyte specific protein tyrosine kinase (blk)

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51451&geneProductId=UniProtKB:P51451

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51451&geneProductId=UniProtKB:P51451

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51451&geneProductId=UniProtKB:P51451

10 September 2018

signaling receptor binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

non-membrane spanning protein tyrosine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

3 references

8 April 2019

8 April 2019

Restoration of the function of bilateral hand grip at the expense of the fingers of the same hand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

protein tyrosine kinase activity

Molecular cloning and chromosomal localization of the human homologue of a B-lymphocyte specific protein tyrosine kinase (blk)

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

8 April 2019

8 April 2019

Nuclear cGAS suppresses DNA repair and promotes tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

cell component

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

1 reference

8 April 2019

extrinsic component of cytoplasmic side of plasma membrane

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

1 reference

8 April 2019

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

1 reference

8 April 2019

B cell receptor signaling pathway

biological process

1 reference

8 April 2019

Restoration of the function of bilateral hand grip at the expense of the fingers of the same hand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

cell differentiation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

intracellular signal transduction

1 reference

8 April 2019

Specific expression of a tyrosine kinase gene, blk, in B lymphoid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

1 reference

8 April 2019

transmembrane receptor protein tyrosine kinase signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

protein phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

1 reference

8 April 2019

regulation of cell population proliferation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51451&geneProductId=UniProtKB:P51451

1 reference

27 March 2018

peptidyl-tyrosine autophosphorylation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

innate immune response

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51451&geneProductId=UniProtKB:P51451

1 reference

27 March 2018

positive regulation of insulin secretion

IMP

1 reference

8 April 2019

Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

IMP

cell migration

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51451&geneProductId=UniProtKB:P51451

1 reference

27 March 2018

regulation of B cell receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

1 reference

8 April 2019

peptidyl-tyrosine phosphorylation

1 reference

8 April 2019

Nuclear cGAS suppresses DNA repair and promotes tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51451

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

6912

language of work or name

English

http://purl.uniprot.org/uniprot/P51451

17 August 2016

Gene Atlas image

PBB GE BLK 206255 at fs.png
732 × 530; 11 KB

0 references

exact match

1 reference

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

SH2 domain

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

Tyrosine-protein kinase Blk, SH2 domain

1 reference