(Q40241223)

English

Amino acid substitutions in the Dictyostelium G alpha subunit G alpha 2 produce dominant negative phenotypes and inhibit the activation of adenylyl cyclase, guanylyl cyclase, and phospholipase C.

scientific article published on July 1992

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Statements

scholarly article

1 reference

Europe PubMed Central

18 September 2017

Amino acid substitutions in the Dictyostelium G alpha subunit G alpha 2 produce dominant negative phenotypes and inhibit the activation of adenylyl cyclase, guanylyl cyclase, and phospholipase C. (English)

1 reference

Europe PubMed Central

18 September 2017

author name string

K Okaichi

1

1 reference

Europe PubMed Central

18 September 2017

A B Cubitt

2

1 reference

Europe PubMed Central

18 September 2017

G S Pitt

3

1 reference

Europe PubMed Central

18 September 2017

R A Firtel

4

1 reference

Europe PubMed Central

18 September 2017

publication date

1 July 1992

1 reference

Europe PubMed Central

18 September 2017

Molecular Biology of the Cell

1 reference

Europe PubMed Central

18 September 2017

3

1 reference

Europe PubMed Central

18 September 2017

735-747

1 reference

Europe PubMed Central

18 September 2017

7

1 reference

Europe PubMed Central

18 September 2017

Identification of regions essential for extrachromosomal replication and maintenance of an endogenous plasmid in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Establishment of a transient expression system for Dictyostelium discoideum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

G protein multiplicity in eukaryotic signal transduction systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

G proteins: transducers of receptor-generated signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

A chemoattractant receptor controls development in Dictyostelium discoideum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Cyclic AMP and other signals controlling cell development and differentiation in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Cyclic AMP regulation of early gene expression in Dictyostelium discoideum: mediation via the cell surface cyclic AMP receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Molecular basis of transmembrane signal transduction in Dictyostelium discoideum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

A Ca2+-dependent signal transduction system participates in coupling expression of some cAMP-dependent prespore genes to the cell surface receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Dictyostelium discoideum: a model system for cell-cell interactions in development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Inositol trisphosphate and diacylglycerol can differentially modulate gene expression in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

The G-protein family and their interaction with receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Mutations in the GTP-binding site of GS alpha alter stimulation of adenylyl cyclase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

G protein linked signal transduction pathways in development: dictyostelium as an experimental system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Two-phase regulatory pathway controls cAMP receptor-mediated expression of early genes in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Multiple alpha subunits of guanine nucleotide-binding proteins in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

The GTPase superfamily: a conserved switch for diverse cell functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Type-specific regulation of adenylyl cyclase by G protein beta gamma subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Dictyostelium transiently expresses eight distinct G-protein alpha-subunits during its developmental program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Diversity of G proteins in signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

The GTPase superfamily: conserved structure and molecular mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Surface cAMP receptors mediate multiple responses during development in Dictyostelium: evidenced by antisense mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

cAMP signal transduction pathways regulating development of Dictyostelium discoideum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Signal transduction pathways controlling multicellular development in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

22 September 2017

Sensory adaptation of Dictyostelium discoideum cells to chemotactic signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

25 September 2017

Cyclic 3', 5'-AMP relay dictyostelium discoideum. V. Adaptation of the cAMP signaling response during cAMP stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

25 September 2017

Phenocopy of discoidin I-minus mutants by antisense transformation in Dictyostelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

Construction of an extrachromosomally replicating transformation vector for Dictyostelium discoideum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

Different molecular mechanisms for cAMP regulation of gene expression during Dictyostelium development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

Differential effects of temperature on cAMP-induced excitation, adaptation, and deadaptation of adenylate and guanylate cyclase in Dictyostelium discoideum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

cAMP regulation of early gene expression in signal transduction mutants of Dictyostelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

Ligand-induced phosphorylation of the cAMP receptor from Dictyostelium discoideum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

Mutant ras gene induces elevated levels of inositol tris- and hexakisphosphates in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

Signal transduction in Dictyostelium fgd A mutants with a defective interaction between surface cAMP receptors and a GTP-binding regulatory protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

GTP analogues stimulate inositol trisphosphate formation transiently in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

Synthesis in Escherichia coli of GTPase-deficient mutants of Gs alpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

Mutation of glycine 49 to valine in the alpha subunit of GS results in the constitutive elevation of cyclic AMP synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

Regulation and function of G alpha protein subunits in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

The extrachromosomal replication of Dictyostelium plasmid Ddp2 requires a cis-acting element and a plasmid-encoded trans-acting factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

A spatial gradient of expression of a cAMP-regulated prespore cell-type-specific gene in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

Expression and characterization of calmodulin-activated (type I) adenylylcyclase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

A Ca2+ transport system associated with the plasma membrane of Dictyostelium discoideum is activated by different chemoattractant receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

A role for cAMP-dependent protein kinase A in early Dictyostelium development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

Gene targeting of the aggregation stage cAMP receptor cAR1 in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

The G226A mutant of Gs alpha highlights the requirement for dissociation of G protein subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

Molecular genetic analysis of two G alpha protein subunits in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

Hormonal stimulation of adenylyl cyclase through Gi-protein beta gamma subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275631

17 June 2018

Determination of inositol 1,4,5-trisphosphate levels in Dictyostelium by isotope dilution assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/1355376

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adaptation to chemotactic cyclic AMP signals in Dictyostelium involves the G-protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/1355376

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP stimulates accumulation of inositol trisphosphate in Dictyostelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/1355376

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmembrane signaling in Dictyostelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/1355376

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of cAMP and adenosine derivatives to Dictyostelium discoideum cells. Relationships of binding, chemotactic, and antagonistic activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/1355376

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo receptor-mediated phosphorylation of a G protein in Dictyostelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/1355376

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.3.7.735

1 reference

Europe PubMed Central

18 September 2017

release_bhj6bse5yzdjhjst7ig6axkdxq

1 reference

https://api.fatcat.wiki/v0/release/bhj6bse5yzdjhjst7ig6axkdxq

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

18 September 2017

1 reference

Europe PubMed Central

18 September 2017

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