(Q40279477)

English

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules

scientific article published on 15 May 2006

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scholarly article

1 reference

Europe PubMed Central

19 September 2017

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules (English)

1 reference

Europe PubMed Central

19 September 2017

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author name string

Celia P Briscoe

1

1 reference

Europe PubMed Central

19 September 2017

Andrew J Peat

2

1 reference

Europe PubMed Central

19 September 2017

Stephen C McKeown

3

1 reference

Europe PubMed Central

19 September 2017

David F Corbett

4

1 reference

Europe PubMed Central

19 September 2017

Aaron S Goetz

5

1 reference

Europe PubMed Central

19 September 2017

Thomas R Littleton

6

1 reference

Europe PubMed Central

19 September 2017

David C McCoy

7

1 reference

Europe PubMed Central

19 September 2017

Terry P Kenakin

8

1 reference

Europe PubMed Central

19 September 2017

John L Andrews

9

1 reference

Europe PubMed Central

19 September 2017

Carina Ammala

10

1 reference

Europe PubMed Central

19 September 2017

James A Fornwald

11

1 reference

Europe PubMed Central

19 September 2017

Diane M Ignar

12

1 reference

Europe PubMed Central

19 September 2017

Stephen Jenkinson

13

1 reference

Europe PubMed Central

19 September 2017

language of work or name

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publication date

15 May 2006

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Europe PubMed Central

19 September 2017

British Journal of Pharmacology

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Europe PubMed Central

19 September 2017

148

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Europe PubMed Central

19 September 2017

619-628

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Europe PubMed Central

19 September 2017

5

1 reference

Europe PubMed Central

19 September 2017

Role of GPR40 in fatty acid action on the beta cell line INS-1E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

Free fatty acid receptor 1 (FFA(1)R/GPR40) and its involvement in fatty-acid-stimulated insulin secretion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

GPR40 gene Arg211His polymorphism may contribute to the variation of insulin secretory capacity in Japanese men

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

A family of fatty acid binding receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

1 reference

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22 September 2017

Heterologous expression of G protein-coupled receptors in U-2 OS osteosarcoma cells

1 reference

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22 September 2017

Palmitate-induced Ca2+-signaling in pancreatic beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs

1 reference

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22 September 2017

Lipoapoptosis: its mechanism and its diseases

1 reference

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22 September 2017

The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190,562 genetic variations in the human genome. Single-nucleotide polymorphism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

A fatty acid- dependent step is critically important for both glucose- and non-glucose-stimulated insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

Efficient generation of infectious recombinant baculoviruses by site-specific transposon-mediated insertion of foreign genes into a baculovirus genome propagated in Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

22 September 2017

Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

25 September 2017

Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

17 June 2018

Signal transduction mechanisms in nutrient-induced insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

17 June 2018

Mechanisms of the stimulation of insulin release by saturated fatty acids. A study of palmitate effects in mouse beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

17 June 2018

Operational models of pharmacological agonism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

17 June 2018

Estimation of the affinities of allosteric ligands using radioligand binding and pharmacological null methods.

1 reference

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17 June 2018

A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic beta-cells

1 reference

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17 June 2018

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

1 reference

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17 June 2018

Reduction in voltage-gated K+ currents in primary cultured rat pancreatic beta-cells by linoleic acids

1 reference

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20 August 2018

The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

20 August 2018

Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

20 August 2018

Palmitate increases L-type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

20 August 2018

Glibenclamide inhibits islet carnitine palmitoyltransferase 1 activity, leading to PKC-dependent insulin exocytosis

1 reference

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20 August 2018

Acute effects of fatty acids on insulin secretion from rat and human islets of Langerhans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751878

20 August 2018

Quantitative trait linkage analysis of lipid-related traits in familial type 2 diabetes: evidence for linkage of triglyceride levels to chromosome 19q.

1 reference

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20 August 2018

Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro

1 reference

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20 August 2018

Identifiers

10.1038/SJ.BJP.0706770

1 reference

Europe PubMed Central

19 September 2017

1 reference

Europe PubMed Central

19 September 2017

1 reference

Europe PubMed Central

19 September 2017

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