(Q40316905)

English

Munc18c mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose stimulated insulin secretion in human pancreatic beta-cells

scientific article published on 16 February 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

Munc18c mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose stimulated insulin secretion in human pancreatic beta-cells (English)

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

1 reference

based on heuristic

inferred from title

author name string

Dan Zhu

1

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

Li Xie

2

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

Negar Karimian

3

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

Tao Liang

4

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

Youhou Kang

5

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

Ya-Chi Huang

6

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

Herbert Y Gaisano

7

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

publication date

16 February 2015

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

Molecular Metabolism

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

4

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

5

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

418-426

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4421095/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Doc2b serves as a scaffolding platform for concurrent binding of multiple Munc18 isoforms in pancreatic islet β-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Munc18c: a controversial regulator of peripheral insulin action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Here come the newcomer granules, better late than never

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Syntaxin 4 up-regulation increases efficiency of insulin release in pancreatic islets from humans with and without type 2 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Exocyst sec5 regulates exocytosis of newcomer insulin granules underlying biphasic insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Munc18b is a major mediator of insulin exocytosis in rat pancreatic β-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Syntaxin-3 regulates newcomer insulin granule exocytosis and compound fusion in pancreatic beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Munc18-1 regulates first-phase insulin release by promoting granule docking to multiple syntaxin isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Dynamics of insulin secretion and the clinical implications for obesity and diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

The syntaxin 4 N terminus regulates its basolateral targeting by munc18c-dependent and -independent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Rim2alpha determines docking and priming states in insulin granule exocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Munc18c depletion selectively impairs the sustained phase of insulin release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Membrane fusion: grappling with SNARE and SM proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

The functions of Munc18-1 in regulated exocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Conformational switch of syntaxin-1 controls synaptic vesicle fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Skeletal muscle munc18c and syntaxin 4 in human obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

VAMP8 is the v-SNARE that mediates basolateral exocytosis in a mouse model of alcoholic pancreatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Munc18-1 is critical for plasma membrane localization of syntaxin1 but not of SNAP-25 in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

SNAREs--engines for membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

MUNC-ing around with insulin action.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Insulin granule dynamics in pancreatic beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic B-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Munc18-1 promotes large dense-core vesicle docking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

A rat brain Sec1 homologue related to Rop and UNC18 interacts with syntaxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Molecular identification of two novel Munc-18 isoforms expressed in non-neuronal tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

22 September 2017

Selective activation of cognate SNAREpins by Sec1/Munc18 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

17 June 2018

Inhibition of insulin-induced GLUT4 translocation by Munc18c through interaction with syntaxin4 in 3T3-L1 adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

17 June 2018

Dual role of VAMP8 in regulating insulin exocytosis and islet β cell growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

20 August 2018

Voltage-gated ion channels in human pancreatic beta-cells: electrophysiological characterization and role in insulin secretion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

20 August 2018

Syntaxin 4 facilitates biphasic glucose-stimulated insulin secretion from pancreatic beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

20 August 2018

Syntaxin 4 transgenic mice exhibit enhanced insulin-mediated glucose uptake in skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

20 August 2018

Insulin resistance in tetracycline-repressible Munc18c transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

20 August 2018

Protein kinase C enhances exocytosis from chromaffin cells by increasing the size of the readily releasable pool of secretory granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4421095

20 August 2018

Role of mammalian homologue of Caenorhabditis elegans unc-13-1 (Munc13-1) in the recruitment of newcomer insulin granules in both first and second phases of glucose-stimulated insulin secretion in mouse islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/25973389

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucagon-like peptide 1 regulates sequential and compound exocytosis in pancreatic islet beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25973389

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MOLMET.2015.02.004

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 September 2017

ResearchGate publication ID

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