(Q40367788)

19 September 2017

Alkyl-substituted polyaminohydroxamic acids: a novel class of targeted histone deacetylase inhibitors (English)

1 reference

19 September 2017

7

1 reference

19 September 2017

Sheeba Varghese

1

1 reference

19 September 2017

Deepak Gupta

2

1 reference

19 September 2017

Tiffany Baran

3

1 reference

19 September 2017

Anchalee Jiemjit

4

1 reference

19 September 2017

Steven D Gore

5

1 reference

19 September 2017

Robert A Casero

6

1 reference

19 September 2017

language of work or name

English

0 references

publication date

1 October 2005

1 reference

Journal of Medicinal Chemistry

19 September 2017

1 reference

19 September 2017

48

1 reference

19 September 2017

6350-6365

1 reference

19 September 2017

20

1 reference

Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer

19 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554812

Trichostatin A-like hydroxamate histone deacetylase inhibitors as therapeutic agents: toxicological point of view

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554812

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554812

Histone deacetylases and cancer: causes and therapies

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554812

Deacetylase enzymes: biological functions and the use of small-molecule inhibitors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554812

Terminally alkylated polyamine analogues as chemotherapeutic agents.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554812

Chemical highlights of polyamine transport

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554812

Synthesis and evaluation of unsymmetrically substituted polyamine analogues as modulators of human spermidine/spermine-N1-acetyltransferase (SSAT) and as potential antitumor agents.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554812

Synthesis and biological evaluation of S-adenosyl-1,12-diamino-3-thio-9-azadodecane, a multisubstrate adduct inhibitor of spermine synthase

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554812

Phase I and pharmacokinetic study of MS-275, a histone deacetylase inhibitor, in patients with advanced and refractory solid tumors or lymphoma

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554812

Long-chain polyamines (oligoamines) exhibit strong cytotoxicities against human prostate cancer cells.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554812

Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)pipe

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554812

A novel polyamine analog (SL-11093) inhibits growth of human prostate tumor xenografts in nude mice

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554812

Different accessibilities in chromatin to histone acetylase

20 August 2018

1 reference

12 December 2020

Polyamines inhibit the yeast histone deacetylase

1 reference

12 December 2020

Structural specificity of polyamines and polyamine analogues in the protection of DNA from strand breaks induced by reactive oxygen species

1 reference

12 December 2020

1-(N-alkylamino)-11-(N-ethylamino)-4,8-diazaundecanes: simple synthetic polyamine analogues that differentially alter tubulin polymerization

1 reference

12 December 2020

Identifiers

DOI

10.1021/JM0505009

1 reference

19 September 2017

1 reference

19 September 2017

1 reference