(Q4037752)

C-type lectin-like/link domain superfamily

1 reference

C-type lectin fold

1 reference

selectin superfamily

1 reference

selectin

1 reference

Sushi/SCR/CCP domain, protein family

1 reference

C-type lectin-like domain, protein family

1 reference

EGF-like domain, protein family

1 reference

EGF-like, conserved site, protein family

1 reference

C-type lectin, conserved site, protein family

1 reference

Lipid raft localization of cell surface E-selectin is required for ligation-induced activation of phospholipase C gamma

1 reference

13 November 2019

1 reference

13 November 2019

phospholipase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

Higher-affinity oligosaccharide ligands for E-selectin

oligosaccharide binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

1 reference

8 April 2019

Endoglycan, a member of the CD34 family of sialomucins, is a ligand for the vascular selectins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

transmembrane signaling receptor activity

IPI

1 reference

8 April 2019

Lipid raft localization of cell surface E-selectin is required for ligation-induced activation of phospholipase C gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

1 reference

8 April 2019

Higher-affinity oligosaccharide ligands for E-selectin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

integral component of membrane

IEA

cell component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

2 references

cortical cytoskeleton

1 reference

8 April 2019

Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

8 April 2019

Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

perinuclear region of cytoplasm

IEA

1 reference

8 April 2019

Lipid raft localization of cell surface E-selectin is required for ligation-induced activation of phospholipase C gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

1 reference

8 April 2019

Lipid raft localization of cell surface E-selectin is required for ligation-induced activation of phospholipase C gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

1 reference

8 April 2019

Clustering endothelial E-selectin in clathrin-coated pits and lipid rafts enhances leukocyte adhesion under flow

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

1 reference

8 April 2019

Clustering endothelial E-selectin in clathrin-coated pits and lipid rafts enhances leukocyte adhesion under flow

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

1 reference

8 April 2019

Circulating endothelial cell adhesion molecules as diagnostic markers for the early identification of pregnant women at risk for development of preeclampsia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

integral component of plasma membrane

1 reference

8 April 2019

Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

leukocyte cell-cell adhesion

biological process

1 reference

8 April 2019

Higher-affinity oligosaccharide ligands for E-selectin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

1 reference

8 April 2019

Clustering endothelial E-selectin in clathrin-coated pits and lipid rafts enhances leukocyte adhesion under flow

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

response to interleukin-1

IMP

1 reference

8 April 2019

Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

positive regulation of receptor internalization

1 reference

8 April 2019

Cytoplasmic domain of E-selectin contains a non-tyrosine endocytosis signal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

actin filament-based process

1 reference

8 April 2019

Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

leukocyte migration involved in inflammatory response

1 reference

8 April 2019

Clustering endothelial E-selectin in clathrin-coated pits and lipid rafts enhances leukocyte adhesion under flow

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

activation of phospholipase C activity

1 reference

8 April 2019

Lipid raft localization of cell surface E-selectin is required for ligation-induced activation of phospholipase C gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

response to tumor necrosis factor

IMP

1 reference

8 April 2019

Clustering endothelial E-selectin in clathrin-coated pits and lipid rafts enhances leukocyte adhesion under flow

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

response to lipopolysaccharide

1 reference

8 April 2019

Clustering endothelial E-selectin in clathrin-coated pits and lipid rafts enhances leukocyte adhesion under flow

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

regulation of inflammatory response

1 reference

8 April 2019

Clustering endothelial E-selectin in clathrin-coated pits and lipid rafts enhances leukocyte adhesion under flow

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

leukocyte tethering or rolling

1 reference

8 April 2019

Clustering endothelial E-selectin in clathrin-coated pits and lipid rafts enhances leukocyte adhesion under flow

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins

IMP

inflammatory response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

calcium-mediated signaling

1 reference

8 April 2019

Lipid raft localization of cell surface E-selectin is required for ligation-induced activation of phospholipase C gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16581

physically interacts with

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1215923

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL3707446

has part(s)

EGF-like, conserved site

1 reference

sushi/SCR/CCP domain

1 reference

EGF-like domain

1 reference

C-type lectin-like domain

1 reference

C-type lectin, conserved site

1 reference

Selectin, C-type lectin-like domain

1 reference

D12.776.395.550.200.700.300

Identifiers

MeSH descriptor ID

D019040

subject named as

E-Selectin

0 references

MeSH tree code

0 references

D12.776.503.843.300

0 references

D12.776.543.550.200.700.300

0 references

D23.050.301.350.700.300

0 references

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference