(Q40448034)

English

Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis.

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scholarly article

1 reference

Europe PubMed Central

20 September 2017

Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis. (English)

1 reference

Europe PubMed Central

20 September 2017

apoptotic process

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author name string

Darcie A Sharp

1

1 reference

Europe PubMed Central

20 September 2017

David A Lawrence

2

1 reference

Europe PubMed Central

20 September 2017

Avi Ashkenazi

3

1 reference

Europe PubMed Central

20 September 2017

language of work or name

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publication date

10 March 2005

1 reference

Europe PubMed Central

20 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

20 September 2017

280

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Europe PubMed Central

20 September 2017

19401-19409

1 reference

Europe PubMed Central

20 September 2017

19

1 reference

Europe PubMed Central

20 September 2017

Cell death: critical control points

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Caspase activation: revisiting the induced proximity model

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

A unified model for apical caspase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Insights into the regulatory mechanism for caspase-8 activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Regulation of lymphocyte proliferation and death by FLIP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

The role of c-FLIP in modulation of CD95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Casper is a FADD- and caspase-related inducer of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Inhibition of death receptor signals by cellular FLIP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Activation of caspases-8 and -10 by FLIP(L).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Interdimer processing mechanism of procaspase-8 activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

CASH, a novel caspase homologue with death effector domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

The short splice form of Casper/c-FLIP is a major cellular inhibitor of TRAIL-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Expression of the cellular FLICE-inhibitory protein (c-FLIP) protects Hodgkin's lymphoma cells from autonomous Fas-mediated death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

FLIP overexpression inhibits death receptor-induced apoptosis in malignant mesothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Persistent c-FLIP(L) expression is necessary and sufficient to maintain resistance to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in prostate cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Caspase-8 serves both apoptotic and nonapoptotic roles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

cFLIP-L inhibits p38 MAPK activation: an additional anti-apoptotic mechanism in bile acid-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413962200

21 January 2018

Identifiers

10.1074/JBC.M413962200

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

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