(Q40454938)

English

Identification of a DEF-type docking domain for extracellular signal-regulated kinases 1/2 that directs phosphorylation and turnover of the BH3-only protein BimEL.

scientific article published on 23 February 2005

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scholarly article

1 reference

Europe PubMed Central

20 September 2017

Identification of a DEF-type docking domain for extracellular signal-regulated kinases 1/2 that directs phosphorylation and turnover of the BH3-only protein BimEL. (English)

1 reference

Europe PubMed Central

20 September 2017

phosphorylation

1 reference

based on heuristic

inferred from title

author name string

Rebecca Ley

1

1 reference

Europe PubMed Central

20 September 2017

Kathryn Hadfield

2

1 reference

Europe PubMed Central

20 September 2017

Elizabeth Howes

3

1 reference

Europe PubMed Central

20 September 2017

Simon J Cook

4

1 reference

Europe PubMed Central

20 September 2017

language of work or name

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publication date

23 February 2005

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Europe PubMed Central

20 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

20 September 2017

280

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Europe PubMed Central

20 September 2017

17657-17663

1 reference

Europe PubMed Central

20 September 2017

18

1 reference

Europe PubMed Central

20 September 2017

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Bim: a novel member of the Bcl-2 family that promotes apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Docking domains and substrate-specificity determination for MAP kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Docking motif interactions in MAP kinases revealed by hydrogen exchange mass spectrometry.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Phosphorylation of the pro-apoptotic protein Bim in lymphocytes is associated with protection from apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Docking sites on substrate proteins direct extracellular signal-regulated kinase to phosphorylate specific residues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412342200

21 January 2018

Identifiers

10.1074/JBC.M412342200

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

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