(Q40464114)

20 September 2017

title

BCL-2: Prevention of Apoptosis as a Mechanism of Drug Resistance (English)

1 reference

https://api.crossref.org/works/10.1016/S0889-8588(18)30104-7

neoplastic gene expression regulation

8 July 2024

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7642473

8 July 2024

author name string

J. C. Reed

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7642473

8 July 2024

publication date

1 April 1995

1 reference

20 September 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7642473

https://api.elsevier.com/content/article/PII:S0889858818301047?httpAccept=text/xml

8 July 2024

work available at URL

1 reference

https://api.crossref.org/works/10.1016/S0889-8588(18)30104-7

https://api.elsevier.com/content/article/PII:S0889858818301047?httpAccept=text/plain

8 July 2024

1 reference

https://api.crossref.org/works/10.1016/S0889-8588(18)30104-7

Hematology / Oncology Clinics of North America

8 July 2024

published in

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20 September 2017

volume

9

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20 September 2017

issue

2

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20 September 2017

page(s)

451-473

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publication type of scholarly work

20 September 2017

review article

1 reference

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

cites work

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Regulation of Bcl-2 expression and apoptosis in acute myeloblastic leukaemia cells by granulocyte-macrophage colony-stimulating factor

8 July 2024

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Thymocyte apoptosis induced by p53-dependent and independent pathways

8 July 2024

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Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents

8 July 2024

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Subcellular localization of the bcl-2 protein in malignant and normal lymphoid cells

8 July 2024

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Stable expression of the calbindin-D28K complementary DNA interferes with the apoptotic pathway in lymphocytes

8 July 2024

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Mechanisms and Functions of Cell Death

8 July 2024

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Activation of the Abelson tyrosine kinase activity is associated with suppression of apoptosis in hemopoietic cells

8 July 2024

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p53 in chronic myelogenous leukemia in acute phase

8 July 2024

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Bcl-2 associates with the ras-related protein R-ras p23

8 July 2024

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Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2.

8 July 2024

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Interleukin 7-dependent B lymphocyte precursor cells are ultrasensitive to apoptosis

8 July 2024

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Bcl-2 functions in an antioxidant pathway to prevent apoptosis

8 July 2024

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bcl-2 rearrangements in de novo diffuse large cell lymphoma. Association with distinctive clinical features

8 July 2024

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Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA.

8 July 2024

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Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

8 July 2024

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Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note

8 July 2024

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Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of bcl-2 gene expression.

8 July 2024

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Transfection with a bcl-2 expression vector protects transplanted bone marrow from chemotherapy-induced myelosuppression

8 July 2024

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Effect of glucocorticosteroid treatment on intracellular calcium homeostasis in mouse lymphoma cells

8 July 2024

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Control of sensitivity to induction of apoptosis in myeloid leukemic cells by differentiation and bcl-2 dependent and independent pathways

8 July 2024

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

8 July 2024

43

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p53 is required for radiation-induced apoptosis in mouse thymocytes

8 July 2024

44

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Bcl-2 proto-oncogene expression in Epstein-Barr-virus-associated nasopharyngeal carcinoma

8 July 2024

45

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How p53 suppresses cell growth

8 July 2024

47

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Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer

8 July 2024

48

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Activation of cyclin A-dependent protein kinases during apoptosis

8 July 2024

50

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The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice

8 July 2024

51

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Identification of a p53-dependent negative response element in the bcl-2 gene

8 July 2024

55

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Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo

8 July 2024

56

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Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice

8 July 2024

57

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18q21 rearrangement in diffuse large cell lymphoma: incidence and clinical significance

8 July 2024

59

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Evaluation of bcl-2 protein expression and 14;18 translocation as prognostic markers in follicular lymphoma

8 July 2024

62

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bcl-2 protein in non-small-cell lung carcinoma

8 July 2024

63

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p53 and bcl-2 expression in high-grade B-cell lymphomas: correlation with survival time

8 July 2024

64

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Bcl-2 and the regulation of programmed cell death

8 July 2024

65

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Regulation of chemoresistance by the bcl-2 oncoprotein in non-Hodgkin's lymphoma and lymphocytic leukemia cell lines

8 July 2024

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The clinical relevance of t(14;18)/BCL-2 rearrangement and DEL 6q in diffuse large cell lymphoma and immunoblastic lymphoma

8 July 2024

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c-myc and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle

8 July 2024

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Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system.

8 July 2024

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bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

8 July 2024

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Inhibition of thymocyte apoptosis and negative antigenic selection in bcl-2 transgenic mice

8 July 2024

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The Bcl-2 protein: a prognostic indicator strongly related to p53 protein in lymph node-negative breast cancer patients.

8 July 2024

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bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

8 July 2024

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Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

8 July 2024

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Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma

8 July 2024

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Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

8 July 2024

81

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p53 function and dysfunction

8 July 2024

82

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Molecular analysis of the t(14;18) chromosomal translocation in malignant lymphomas

8 July 2024

86

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Cell death: the significance of apoptosis

8 July 2024

87

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BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

8 July 2024

88

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bcl-2 and other genomic alterations in the prognosis of large-cell lymphoma

8 July 2024

89

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Induction of cellular p53 activity by DNA-damaging agents and growth arrest.

8 July 2024

91

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8 July 2024

Identifiers

1 reference