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Phosphorylation of a novel SOCS-box regulates assembly of the HIV-1 Vif-Cul5 complex that promotes APOBEC3G degradation
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Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
title
Phosphorylation of a novel SOCS-box regulates assembly of the HIV-1 Vif-Cul5 complex that promotes APOBEC3G degradation
(English)
1 reference
stated in
Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
main subject
HIV
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phosphorylation
0 references
author
Joao Goncalves
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
Mariana Santa-Marta
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
Andrew Mehle
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1
object named as
Andrew Mehle
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stated in
Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
author name string
Mark McPike
series ordinal
4
1 reference
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Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
Dana Gabuzda
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
publication date
1 December 2004
1 reference
stated in
Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
published in
Genes & Development
1 reference
stated in
Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
volume
18
1 reference
stated in
Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
page(s)
2861-2866
1 reference
stated in
Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
issue
23
1 reference
stated in
Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
cites work
The viral infectivity factor (Vif) of HIV-1 unveiled
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Tyrosine-phosphorylated SOCS3 interacts with the Nck and Crk-L adapter proteins and regulates Nck activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Vif overcomes the innate antiviral activity of APOBEC3G by promoting its degradation in the ubiquitin-proteasome pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
HIV-1 Vif Blocks the Antiviral Activity of APOBEC3G by Impairing Both Its Translation and Intracellular Stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
DNA deamination mediates innate immunity to retroviral infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Natural substrates of the proteasome and their recognition by the ubiquitin system.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
The SOCS box: a tale of destruction and degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Pim serine/threonine kinases regulate the stability of Socs-1 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Mitogen-activated protein kinase phosphorylates and regulates the HIV-1 Vif protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated Cis protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Phosphorylation of Vif and its role in HIV-1 replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Subcellular localization of the Vif protein of human immunodeficiency virus type 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Subcellular localization specified by protein acylation and phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
22 September 2017
The Vif Protein of HIV Triggers Degradation of the Human Antiretroviral DNA Deaminase APOBEC3G
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534646
retrieved
20 August 2018
Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15574592
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1101/GAD.1249904
1 reference
stated in
Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
PMCID
534646
1 reference
stated in
Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
PubMed ID
15574592
1 reference
stated in
Europe PubMed Central
PMCID
534646
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
ResearchGate publication ID
8152250
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