(Q40504292)

21 September 2017

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title

Generation of mutagens during arachidonic acid metabolism (English)

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21 September 2017

L J Marnett

1

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21 September 2017

1 December 1994

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Cancer and Metastasis Reviews

21 September 2017

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21 September 2017

13

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21 September 2017

303-308

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21 September 2017

3-4

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https://scigraph.springernature.com/pub.10.1007/bf00666100

21 September 2017

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cites work

Unequivocal demonstration that malondialdehyde is a mutagen

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12 December 2020

A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy

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12 December 2020

Activation of some aromatic amines to mutagenic products by prostaglandin endoperoxide synthetase.

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12 December 2020

Purified prostaglandin synthase activates aromatic amines to derivatives that are mutagenic to Salmonella typhimurium

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12 December 2020

Conversion of prostaglandin endoperoxides to C17-hydroxy acids catalyzed by human platelet thromboxane synthase

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12 December 2020

NTP Toxicology and Carcinogenesis Studies of Malonaldehyde, Sodium Salt (3-Hydroxy-2-propenal, Sodium Salt) (CAS No. 24382-04-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

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12 December 2020

Studies of the reaction of malondialdehyde with cytosine nucleosides

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12 December 2020

Hematin-catalyzed epoxidation of 7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene by polyunsaturated fatty acid hydroperoxides.

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12 December 2020

Comparative effects of prostaglandin H synthase-catalyzed binding of two 5-nitrofuran urinary bladder carcinogens.

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12 December 2020

Prostaglandin-H synthase containing cell lines as tools for studying metabolism and toxicity of xenobiotics

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12 December 2020

Mutagenic response of mouse lymphoma cells after activation of benzidine and 2-aminofluorene with purified prostaglandin H synthase

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12 December 2020

Mutagenicity and cytotoxicity of malonaldehyde in mammalian cells

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12 December 2020

Inhibition by aspirin of N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide-induced bladder carcinogenesis and enhancement of forestomach carcinogenesis

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12 December 2020

Oxidation of substituted N,N-dimethylanilines by cytochrome P-450: estimation of the effective oxidation-reduction potential of cytochrome P-450.

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12 December 2020

p53 mutations in human cancers

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12 December 2020

The 'A rule' of mutagen specificity: a consequence of DNA polymerase bypass of non-instructional lesions?

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12 December 2020

The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1

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12 December 2020

Prostaglandin H synthase and xenobiotic oxidation

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12 December 2020

Oxygen radical-dependent epoxidation of (7S,8S)-dihydroxy-7,8-dihydrobenzo[a]pyrene in mouse skin in vivo. Stimulation by phorbol esters and inhibition by antiinflammatory steroids

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12 December 2020

Polycyclic aromatic hydrocarbon oxidation during prostaglandin biosynthesis

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12 December 2020

Mutagenicity of malonaldehyde, a decomposition product of peroxidized polyunsaturated fatty acids

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12 December 2020

High-performance liquid chromatography with electrochemical detection for determination of the major malondialdehyde-guanine adduct

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12 December 2020

A genetic model for colorectal tumorigenesis

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12 December 2020

Analysis of the malondialdehyde-2'-deoxyguanosine adduct in rat liver DNA by gas chromatography/electron capture negative chemical ionization mass spectrometry

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12 December 2020

Investigation of the adducts formed by reaction of malondialdehyde with adenosine

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12 December 2020

Bioactivation of xenobiotics by prostaglandin H synthase

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12 December 2020

Determination of malonaldehyde-modified 2'-deoxyguanosine-3'-monophosphate and DNA by 32P-postlabelling

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12 December 2020

Spectral properties of the higher oxidation states of prostaglandin H synthase

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12 December 2020

Naturally occurring carbonyl compounds are mutagens in Salmonella tester strain TA104.

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12 December 2020

Arachidonic acid-dependent peroxidative activation of carcinogenic arylamines by extrahepatic human tissue microsomes

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12 December 2020

In vitro bioactivation of phenytoin to a reactive free radical intermediate by prostaglandin synthetase, horseradish peroxidase, and thyroid peroxidase

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12 December 2020

On the mechanism of the biosynthesis of prostaglandins E-1 and F-1-alpha

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12 December 2020

DNA sequence analysis of spontaneous and beta-methoxy-acrolein-induced mutations in Salmonella typhimurium hisD3052.

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12 December 2020

Identification of adducts formed by reaction of guanine nucleosides with malondialdehyde and structurally related aldehydes

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12 December 2020

Polyunsaturated fatty acid alkoxyl radicals exist as carbon-centered epoxyallylic radicals: a key step in hydroperoxide-amplified lipid peroxidation

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12 December 2020

Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury

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12 December 2020

Dissociation of malondialdehyde mutagenicity in Salmonella typhimurium from its ability to induce interstrand DNA cross-links.

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12 December 2020

Mechanisms of cytochrome P-450 catalysis

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12 December 2020

Cooxidation of cyclophosphamide as an alternative pathway for its bioactivation and lung toxicity

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12 December 2020

Role of inflammatory cells in the metabolic activation of polycyclic aromatic hydrocarbons in mouse skin.

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12 December 2020

The reaction between thiobarbituric acid and the oxidation products of certain lipides

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12 December 2020

Prostaglandin synthetase dependent activation of 7,8-dihydro-7,8-dihydroxy-benzo(a)pyrene to mutagenic derivatives

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12 December 2020

Prostaglandin H synthase kinetics. The effect of substituted phenols on cyclooxygenase activity and the substituent effect on phenolic peroxidatic activity

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00666100

1 reference

PubMed ID

7712592

Dimensions Publication ID

21 September 2017

0 references

1 reference

PubMed ID

7712592