(Q40513940)

21 September 2017

Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics (English)

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21 September 2017

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Dan C McManus

1

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21 September 2017

Charles A Lefebvre

2

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21 September 2017

Gabriele Cherton-Horvat

3

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21 September 2017

Martine St-Jean

4

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21 September 2017

Ekambar R Kandimalla

5

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21 September 2017

Sudhir Agrawal

6

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21 September 2017

Stephen J Morris

7

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21 September 2017

Jon P Durkin

8

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21 September 2017

Eric C Lacasse

9

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21 September 2017

language of work or name

English

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publication date

1 October 2004

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21 September 2017

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21 September 2017

23

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21 September 2017

8105-8117

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21 September 2017

49

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207967

21 September 2017

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cites work

Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: in vitro and in vivo studies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Human ICE/CED-3 protease nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Caspase-3 is a component of Fas death-inducing signaling complex in lipid rafts and its activity is required for complete caspase-8 activation during Fas-mediated cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Role of XIAP in the malignant phenotype of transitional cell cancer (TCC) and therapeutic activity of XIAP antisense oligonucleotides against multidrug-resistant TCC in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Structural basis of caspase-7 inhibition by XIAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

The Bcl2 family: regulators of the cellular life-or-death switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Identification of caspase-independent apoptosis in epithelial and cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Killing the messenger: short RNAs that silence gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Real time quantitative PCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Cloning and characterization of the rat homologues of the Inhibitor of Apoptosis protein 1, 2, and 3 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

The inhibitors of apoptosis: there is more to life than Bcl2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Life and death decisions: the role of the IAPs in modulating programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Apoptosis-targeted therapies for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Structural basis for the inhibition of caspase-3 by XIAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

TRAIL: a potential agent for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Mechanisms of caspase activation and inhibition during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Activation of the interferon system by short-interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Reprieval from execution: the molecular basis of caspase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

A single BIR domain of XIAP sufficient for inhibiting caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Expression and biological activity of X-linked inhibitor of apoptosis (XIAP) in human malignant glioma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Induction of an interferon response by RNAi vectors in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

Caspase-independent cell death in AML: caspase inhibition in vitro with pan-caspase inhibitors or in vivo by XIAP or Survivin does not affect cell survival or prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

7 January 2021

XIAP, the guardian angel

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

7 January 2021

Bcl-X(L) expression and its downregulation by a novel retinoid in breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

7 January 2021

Structural Basis of Caspase Inhibition by XIAP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

7 January 2021

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

7 January 2021

Involvement of the bcl-2 gene in human follicular lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207967

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207967

1 reference

Dimensions Publication ID

21 September 2017

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1 reference