(Q40529830)

21 September 2017

Cancer cachexia is regulated by selective targeting of skeletal muscle gene products (English)

1 reference

21 September 2017

Swarnali Acharyya

1

1 reference

21 September 2017

Katherine J Ladner

2

1 reference

21 September 2017

Lori L Nelsen

3

1 reference

21 September 2017

Jeffrey Damrauer

4

1 reference

21 September 2017

Peter J Reiser

5

1 reference

21 September 2017

Steven Swoap

6

1 reference

21 September 2017

Denis C Guttridge

7

1 reference

21 September 2017

language of work or name

English

0 references

publication date

1 August 2004

1 reference

Journal of Clinical Investigation

21 September 2017

1 reference

21 September 2017

114

1 reference

21 September 2017

370-378

1 reference

21 September 2017

3

1 reference

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors

21 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

TNF-alpha increases ubiquitin-conjugating activity in skeletal muscle by up-regulating UbcH2/E220k

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Cancer cachexia: the molecular mechanisms

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Tumor necrosis factor-regulated biphasic activation of NF-kappa B is required for cytokine-induced loss of skeletal muscle gene products

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Cachexia in cancer patients

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Striated muscle cytoarchitecture: an intricate web of form and function

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

IL-6-like cytokines and cancer cachexia: consequences of chronic inflammation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

The divergent effects of tumour necrosis factor-alpha on skeletal muscle: implications in wasting.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Interleukin-15 antagonizes muscle protein waste in tumour-bearing rats

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Role of a proteolysis-inducing factor (PIF) in cachexia induced by a human melanoma (G361).

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

The syndrome of anorexia-cachexia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

The role of cytokines in cancer cachexia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

A critical role for the RelA subunit of nuclear factor kappaB in regulation of multiple immune-response genes and in Fas-induced cell death

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

In vivo analysis of the myosin heavy chain IIB promoter region

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Growth and muscle defects in mice lacking adult myosin heavy chain genes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Characterization of a cancer cachectic factor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Tumor necrosis factor-alpha mediates changes in tissue protein turnover in a rat cancer cachexia model

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Suramin interferes with interleukin-6 receptor binding in vitro and inhibits colon-26-mediated experimental cancer cachexia in vivo

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Nutrition and cancer: physiological interrelationships

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

A phase I study of recombinant interleukin 2 plus recombinant beta-interferon

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Evidence for the involvement of interleukin 6 in experimental cancer cachexia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Altered expression of skeletal muscle myosin isoforms in cancer cachexia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-kappaB.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

NF-kappaB mediates the protein loss induced by TNF-alpha in differentiated skeletal muscle myotubes

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Through thick and thin: wasting, obesity, and TNF alpha

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Tumor necrosis factor, other cytokines and disease

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Phase II study of recombinant human interferon gamma for treatment of cutaneous T-cell lymphoma

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Skeletal muscle myocytes undergo protein loss and reactive oxygen-mediated NF-kappaB activation in response to tumor necrosis factor alpha

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Is TNF really involved in cachexia?

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

An E-box within the MHC IIB gene is bound by MyoD and is required for gene expression in fast muscle.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Mechanisms of experimental cancer cachexia. Local involvement of IL-1 in colon-26 tumor.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Increase in levels of polyubiquitin and proteasome mRNA in skeletal muscle during starvation and denervation atrophy

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Tumors secreting human TNF/cachectin induce cachexia in mice

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Interleukin 1 and tumor necrosis factor do not regulate protein balance in skeletal muscle.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Leptin role in advanced lung cancer. A mediator of the acute phase response or a marker of the status of nutrition?

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Sepsis stimulates release of myofilaments in skeletal muscle by a calcium-dependent mechanism.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Association between tumor necrosis factor in serum and cachexia in patients with prostate cancer.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=484974

Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states

20 August 2018

1 reference

12 December 2020

The fine structure of type II muscle fiber atrophy

1 reference

12 December 2020

Increased ATP-ubiquitin-dependent proteolysis in skeletal muscles of tumor-bearing rats

1 reference

12 December 2020

Molecular analysis of the cytokine network involved in cachexia in colon 26 adenocarcinoma-bearing mice

1 reference

12 December 2020

Protein synthesis measured in vivo in muscle and liver of cachectic tumor-bearing mice

1 reference

12 December 2020

Limited impact of total parenteral nutrition on nutritional status during treatment for small cell lung cancer

1 reference

12 December 2020

Cachectin/tumour-necrosis-factor production by cancer patients

1 reference

12 December 2020

EVIDENCE FOR TUMOUR NECROSIS FACTOR/CACHECTIN PRODUCTION IN CANCER

1 reference

12 December 2020

Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins

1 reference

12 December 2020

Role of endogenous tumor necrosis factor alpha and interleukin 1 for experimental tumor growth and the development of cancer cachexia

1 reference

12 December 2020

Severe cachexia in mice inoculated with interferon-gamma-producing tumor cells

1 reference

12 December 2020

Tumor necrosis factor-alpha and basic fibroblast growth factor differentially inhibit the insulin-like growth factor-I induced expression of myogenin in C2C12 myoblasts

1 reference

12 December 2020

Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells

1 reference

12 December 2020

Serum levels of tumor necrosis factor-alpha and nutritional status in pancreatic cancer patients

1 reference

12 December 2020

Activation of the ATP-ubiquitin-proteasome pathway in skeletal muscle of cachectic rats bearing a hepatoma

1 reference

12 December 2020

Importance of the ATP-ubiquitin-proteasome pathway in the degradation of soluble and myofibrillar proteins in rabbit muscle extracts

1 reference

12 December 2020

Role of TNF receptor 1 in protein turnover during cancer cachexia using gene knockout mice

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI200420174

1 reference

21 September 2017

1 reference

21 September 2017

1 reference