(Q40543086)

21 September 2017

B-RAF is a therapeutic target in melanoma. (English)

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21 September 2017

12

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21 September 2017

Caroline J Springer

11

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author name string

Maria Karasarides

1

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21 September 2017

Antonio Chiloeches

2

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21 September 2017

Robert Hayward

3

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21 September 2017

Dan Niculescu-Duvaz

4

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21 September 2017

Ian Scanlon

5

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21 September 2017

Frank Friedlos

6

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21 September 2017

Lesley Ogilvie

7

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21 September 2017

Douglas Hedley

8

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21 September 2017

Jan Martin

9

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21 September 2017

Christopher J Marshall

10

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21 September 2017

language of work or name

English

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publication date

1 August 2004

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21 September 2017

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21 September 2017

23

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21 September 2017

6292-6298

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21 September 2017

37

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207785

21 September 2017

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cites work

Role of Raf in vascular protection from distinct apoptotic stimuli

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

Lack of BRAF mutation in primary uveal melanoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

Mutations of the BRAF gene in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

MEK kinase activity is not necessary for Raf-1 function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

Abrogation of c-Raf expression induces apoptosis in tumor cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

Discovery of a novel Raf kinase inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

The MEK1 inhibitor PD98059 sensitizes C8161 melanoma cells to cisplatin-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

RAF/RAS oncogenes and mismatch-repair status

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

BRAF as a potential therapeutic target in melanoma and other malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

V599EB-RAF is an oncogene in melanocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

Endothelial apoptosis in Braf-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207785

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207785

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Dimensions Publication ID

21 September 2017

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1 reference