(Q40559949)

English

A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation.

scientific article published on 29 April 2004

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scholarly article

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28 December 2019

A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation (English)

1 reference

Europe PubMed Central

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28 December 2019

Pascal Peschard

1

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28 December 2019

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Noboru Ishiyama

2

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28 December 2019

Tong Lin

3

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28 December 2019

Stan Lipkowitz

4

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28 December 2019

Morag Park

5

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28 December 2019

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29 April 2004

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28 December 2019

Journal of Biological Chemistry

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28 December 2019

279

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28 December 2019

29565-29571

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28 December 2019

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28 December 2019

Beyond the RING: CBL proteins as multivalent adapters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Cbl: many adaptations to regulate protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Molecular cloning and characterization of a novel cbl-family gene, cbl-c

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

cbl-3: a new mammalian cbl family protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

c-Cbl associates directly with the C-terminal tail of the receptor for the macrophage colony-stimulating factor, c-Fms, and down-modulates this receptor but not the viral oncogene v-Fms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Hepatocyte growth factor/scatter factor-Met signaling in tumorigenicity and invasion/metastasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Coendocytosis of cadherin and c-Met coupled to disruption of cell-cell adhesion in MDCK cells--regulation by Rho, Rac and Rab small G proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

InIB-dependent internalization of Listeria is mediated by the Met receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Alternative splicing generates isoforms of the met receptor tyrosine kinase which undergo differential processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Cbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Profiling the global tyrosine phosphorylation state by Src homology 2 domain binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Phosphorylation of tyrosine residues in the kinase domain and juxtamembrane region regulates the biological and catalytic activities of Eph receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Raster3D: photorealistic molecular graphics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403954200

21 January 2018

Identifiers

10.1074/JBC.M403954200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15123609%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15123609%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

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