(Q40566152)

21 September 2017

Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks (English)

1 reference

21 September 2017

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Sukhdev S Brar

1

1 reference

21 September 2017

Mary Watson

series ordinal

2

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21 September 2017

Marilyn Diaz

series ordinal

3

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21 September 2017

language of work or name

English

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publication date

15 April 2004

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Journal of Biological Chemistry

21 September 2017

7

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based on heuristic

inferred from page(s)

published in

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21 September 2017

279

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21 September 2017

26395-26401

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21 September 2017

25

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Variability in the Lambda Light Chain Sequences of Mouse Antibody

21 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

AID mediates hypermutation by deaminating single stranded DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Transcription-coupled events associating with immunoglobulin switch region chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

DNA double-strand breaks: prior to but not sufficient in targeting hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

The activation-induced deaminase functions in a postcleavage step of the somatic hypermutation process

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

DNA double strand breaks occur independent of AID in hypermutating Ig genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Constitutive expression of AID leads to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Activation-induced cytidine deaminase expression in follicular lymphoma: association between AID expression and ongoing mutation in FL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Transport into and out of the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

A simple technique for quantitation of low levels of DNA damage in individual cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Polymerase eta deficiency in the xeroderma pigmentosum variant uncovers an overlap between the S phase checkpoint and double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Visualization of focal nuclear sites of DNA repair synthesis induced by bleomycin in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Dephosphorylation of histone gamma-H2AX during repair of DNA double-strand breaks in mammalian cells and its inhibition by calyculin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Does AID need another aid?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

AID mutant analyses indicate requirement for class-switch-specific cofactors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Somatic mutation hotspots correlate with DNA polymerase eta error spectrum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Transcription-coupled mutagenesis by the DNA deaminase AID

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

Decreased Frequency of Somatic Hypermutation and Impaired Affinity Maturation but Intact Germinal Center Formation in Mice Expressing Antisense RNA to DNA Polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403503200

21 January 2018

Identifiers

DOI

10.1074/JBC.M403503200

1 reference

21 September 2017

1 reference