(Q40626795)

22 September 2017

E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models (English)

1 reference

22 September 2017

1 reference

1 reference

3

1 reference

22 September 2017

Yaohe Wang

1

1 reference

22 September 2017

Gunnel Hallden

2

1 reference

22 September 2017

Arthi Anand

4

1 reference

22 September 2017

Ta-Chiang Liu

5

1 reference

22 September 2017

Jennelle Francis

6

1 reference

22 September 2017

Gabriel Brooks

7

1 reference

22 September 2017

Nick Lemoine

8

1 reference

22 September 2017

David Kirn

9

1 reference

22 September 2017

12 October 2003

1 reference

22 September 2017

1 reference

22 September 2017

21

1 reference

22 September 2017

1328-1335

1 reference

22 September 2017

11

1 reference

https://scigraph.springernature.com/pub.10.1038/nbt887

22 September 2017

0 references

cites work

Replication-selective virotherapy for cancer: Biological principles, risk management and future directions

1 reference

7 January 2021

Replication-selective microbiological agents: fighting cancer with targeted germ warfare

1 reference

7 January 2021

Replication-selective oncolytic adenoviruses: virotherapy aimed at genetic targets in cancer

1 reference

7 January 2021

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

1 reference

7 January 2021

ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

1 reference

7 January 2021

An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy

1 reference

7 January 2021

A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy

1 reference

7 January 2021

A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

1 reference

7 January 2021

Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC1 antigen.

1 reference

7 January 2021

Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents

1 reference

7 January 2021

Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein

1 reference

7 January 2021

Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy

1 reference

7 January 2021

Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned?

1 reference

7 January 2021

Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer

1 reference

7 January 2021

Adenovirus proteins that subvert host defenses

1 reference

7 January 2021

Efficacy of a replication-competent adenovirus (ONYX-015) following intratumoral injection: intratumoral spread and distribution effects

1 reference

7 January 2021

A mouse model for investigating the molecular pathogenesis of adenovirus pneumonia

1 reference

7 January 2021

Adenovirus E3-10.4K/14.5K protein complex inhibits tumor necrosis factor-induced translocation of cytosolic phospholipase A2 to membranes

1 reference

7 January 2021

Adenovirus RIDbeta subunit contains a tyrosine residue that is critical for RID-mediated receptor internalization and inhibition of Fas- and TRAIL-induced apoptosis

1 reference

7 January 2021

Infection of Mouse Liver by Human Adenovirus Type 5

1 reference

7 January 2021

Productive replication of human adenoviruses in mouse epidermal cells

1 reference

7 January 2021

Adenovirus early region 3(E3) immunomodulatory genes decrease the incidence of autoimmune diabetes in NOD mice.

1 reference

7 January 2021

The adenovirus E3 14.7-kilodalton protein which inhibits cytolysis by tumor necrosis factor increases the virulence of vaccinia virus in a murine pneumonia model.

1 reference

7 January 2021

Heterologous expression of adenovirus E3-gp19K in an E1a-deleted adenovirus vector inhibits MHC I expression in vitro, but does not prolong transgene expression in vivo

1 reference

7 January 2021

Fas- and tumor necrosis factor receptor 1-dependent but not perforin-dependent pathways cause injury in livers infected with an adenovirus construct in mice

1 reference

7 January 2021

The adenovirus E3-14.7K protein and the E3-10.4K/14.5K complex of proteins, which independently inhibit tumor necrosis factor (TNF)-induced apoptosis, also independently inhibit TNF-induced release of arachidonic acid

1 reference

7 January 2021

Novel immunocompetent murine tumor models for the assessment of replication-competent oncolytic adenovirus efficacy.

1 reference

7 January 2021

Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial

1 reference

7 January 2021

Cytolysis of adenovirus-infected murine fibroblasts by IFN-gamma-primed macrophages is TNF- and contact-dependent

1 reference

7 January 2021

Gene delivery from replication-selective viruses: arming guided missiles in the war against cancer

1 reference

7 January 2021

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

1 reference

7 January 2021

Local and distant recurrences in rectal cancer patients are predicted by the nonspecific immune response; specific immune response has only a systemic effect--a histopathological and immunohistochemical study

1 reference

7 January 2021

Identifiers

DOI

10.1038/NBT887

1 reference

Dimensions Publication ID

22 September 2017

0 references

1 reference