(Q40631985)

22 September 2017

Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling (English)

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22 September 2017

1

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22 September 2017

3

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22 September 2017

John G Collard

2

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PubMed ID

14506233

22 September 2017

language of work or name

English

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publication date

23 September 2003

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Journal of Biological Chemistry

22 September 2017

7

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based on heuristic

inferred from page(s)

published in

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22 September 2017

278

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22 September 2017

50442-50448

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22 September 2017

50

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Rho GTPases and the actin cytoskeleton

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Rho-family GTPases in cadherin-mediated cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

21 January 2018

RHO-GTPases and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Rho GTPases control polarity, protrusion, and adhesion during cell movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Rac recruits high-affinity integrin alphavbeta3 to lamellipodia in endothelial cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Rho GTPases are over-expressed in human tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Small GTPase Rac1: structure, localization, and expression of the human gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Inhibition of invasion of epithelial cells by Tiam1-Rac signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Spatio-temporal regulation of Rac1 localization and lamellipodia dynamics during epithelial cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Dissociation of GDP dissociation inhibitor and membrane translocation are required for efficient activation of Rac by the Dbl homology-pleckstrin homology region of Tiam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

The Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

A Rac1 effector site controlling mitogenesis through superoxide production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Characterization of a Rac1- and RhoGDI-associated lipid kinase signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Structure of the TPR domain of p67phox in complex with Rac.GTP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Redox-dependent downregulation of Rho by Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

Rac "insert region" is a novel effector region that is implicated in the activation of NADPH oxidase, but not PAK65

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308215200

21 January 2018

Identifiers

DOI

10.1074/JBC.M308215200

1 reference

22 September 2017

1 reference

PubMed ID

14506233