(Q40653974)

reason for preferred rank

22 September 2017

Activated Gαq Inhibits p110α Phosphatidylinositol 3-Kinase and Akt (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M212232200

25 December 2023

Activated G alpha q inhibits p110 alpha phosphatidylinositol 3-kinase and Akt (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12704201

phosphoinositide-3 kinase inhibitor

25 December 2023

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12704201

25 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M212232200

25 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M212232200

25 December 2023

author name string

Hong-Ying Lin

2

1 reference

22 September 2017

Gaofeng Fan

3

1 reference

22 September 2017

Ya-Ping Jiang

4

1 reference

22 September 2017

Lisa M. Ballou

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12704201

25 December 2023

Richard Z. Lin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12704201

25 December 2023

language of work or name

English

0 references

publication date

18 April 2003

1 reference

full work available at URL

22 September 2017

http://www.jbc.org/content/278/26/23472.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12704201

https://api.elsevier.com/content/article/PII:S002192582086147X?httpAccept=text/xml

25 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M212232200

https://api.elsevier.com/content/article/PII:S002192582086147X?httpAccept=text/plain

25 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M212232200

https://syndication.highwire.org/content/doi/10.1074/jbc.M212232200

25 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M212232200

Journal of Biological Chemistry

25 December 2023

published in

1 reference

22 September 2017

278

1 reference

22 September 2017

23472-23479

1 reference

22 September 2017

26

1 reference

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

A function for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in fibroblasts during mitogenesis: requirement for insulin- and lysophosphatidic acid-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Mechanism of activation and function of protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Dual regulation of Akt/protein kinase B by heterotrimeric G protein subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

A Novel Mitogenic Signaling Pathway of Bradykinin in the Human Colon Carcinoma Cell Line SW-480 Involves Sequential Activation of a Gq/11 Protein, Phosphatidylinositol 3-Kinase , and Protein Kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Endothelin-1-induced GLUT4 translocation is mediated via Galpha(q/11) protein and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Muscarinic receptors mediate phospholipase C-dependent activation of protein kinase B via Ca2+, ErbB3, and phosphoinositide 3-kinase in 1321N1 astrocytoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Alpha1 adrenergic receptors activate phosphatidylinositol 3-kinase in human vascular smooth muscle cells. Role in mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Thrombin receptors modulate insulin-stimulated phosphatidylinositol 3,4,5-trisphosphate accumulation in 1321N1 astrocytoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Cross-talk between the insulin and angiotensin signaling systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Differential regulation of the phosphatidylinositol 3-kinase/Akt and p70 S6 kinase pathways by the alpha(1A)-adrenergic receptor in rat-1 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Dual regulation of glycogen synthase kinase-3beta by the alpha1A-adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Evaluation of the pharmacological selectivity profile of alpha 1 adrenoceptor antagonists at prostatic alpha 1 adrenoceptors: binding, functional and in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Identification and quantification of polyphosphoinositides produced in response to platelet-derived growth factor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

G alpha-q/11 protein plays a key role in insulin-induced glucose transport in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

A novel role for phosphatidylinositol 3-kinase beta in signaling from G protein-coupled receptors to Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

The trimeric GTP-binding protein (G(q)/G(11)) alpha subunit is required for insulin-stimulated GLUT4 translocation in 3T3L1 adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Constitutively active Galphaq and Galpha13 trigger apoptosis through different pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

cAMP stimulates protein kinase B in a Wortmannin-insensitive manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

G-Protein-coupled receptors and Fcgamma-receptors mediate activation of Akt/protein kinase B in human phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Gastrin stimulates tyrosine phosphorylation of insulin receptor substrate 1 and its association with Grb2 and the phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Angiotensin II activates phosphatidylinositol 3-kinase in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Serotonin (5-Hydroxytryptamine), a novel regulator of glucose transport in rat skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

Endothelin-1 modulates insulin signaling through phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212232200

American Journal of Physiology

21 January 2018

16

276

H1927

Takahashi

1999

1 reference

https://api.crossref.org/works/10.1074/JBC.M212232200

Journal of Pharmacology and Experimental Therapeutics

25 December 2023

31

272

134

Schwinn

1995

1 reference

https://api.crossref.org/works/10.1074/JBC.M212232200

Journal of Pharmacology and Experimental Therapeutics

25 December 2023

32

284

576

Ruan

1998

1 reference

https://api.crossref.org/works/10.1074/JBC.M212232200

25 December 2023

Identifiers

1 reference

22 September 2017

1 reference