(Q40662652)

22 September 2017

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. (English)

1 reference

22 September 2017

1 reference

Rebecca Ley

1

1 reference

22 September 2017

Kathryn Balmanno

2

1 reference

22 September 2017

Kathryn Hadfield

3

1 reference

22 September 2017

Claire Weston

4

1 reference

22 September 2017

Simon J Cook

5

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22 September 2017

language of work or name

English

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publication date

19 March 2003

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

278

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22 September 2017

18811-18816

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22 September 2017

21

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The Bcl2 family: regulators of the cellular life-or-death switch

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Molecular cloning of a novel polypeptide, DP5, induced during programmed neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Rsk1 mediates a MEK-MAP kinase cell survival signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Cell-cycle arrest by PD184352 requires inhibition of extracellular signal-regulated kinases (ERK) 1/2 but not ERK5/BMK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Bim: a novel member of the Bcl-2 family that promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

PUMA induces the rapid apoptosis of colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

Association of the atypical protein kinase C-interacting protein p62/ZIP with nerve growth factor receptor TrkA regulates receptor trafficking and Erk5 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301010200

21 January 2018

Identifiers

DOI

10.1074/JBC.M301010200

1 reference

22 September 2017

1 reference