(Q40669638)

English

Mutation of threonine 766 in the epidermal growth factor receptor reveals a hotspot for resistance formation against selective tyrosine kinase inhibitors

scientific article published on 19 February 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Mutation of threonine 766 in the epidermal growth factor receptor reveals a hotspot for resistance formation against selective tyrosine kinase inhibitors (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

author name string

Stephanie Blencke

1

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Axel Ullrich

2

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Henrik Daub

3

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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publication date

19 February 2003

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Europe PubMed Central

PubMed publication ID

22 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

22 September 2017

278

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Europe PubMed Central

PubMed publication ID

22 September 2017

17

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

15435-15440

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Receptor protein-tyrosine kinases and their signal transduction pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Vertebrate non-receptor protein-tyrosine kinase families

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Receptor tyrosine kinase signalling as a target for cancer intervention strategies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Rational therapeutic intervention in cancer: kinases as drug targets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

STI571 (Gleevec) as a paradigm for cancer therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

New-age drug meets resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

The ErbB receptor family: a therapeutic target for cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Signal characteristics of G protein-transactivated EGF receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Production of high-titer helper-free retroviruses by transient transfection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Rac/Cdc42 and p65PAK regulate the microtubule-destabilizing protein stathmin through phosphorylation at serine 16

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Epidermal growth factor receptor tyrosine kinase phosphorylation of glucose-6-phosphate dehydrogenase in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Signal transduction by receptors with tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Tyrosine kinase inhibition: an approach to drug development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Protein modules and signalling networks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

New insights into the control of MAP kinase pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: a prospective study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Strain-dependent epithelial defects in mice lacking the EGF receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211158200

21 January 2018

Identifiers

10.1074/JBC.M211158200

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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