(Q40696914)

22 September 2017

DNA damage-induced translocation of the Werner helicase is regulated by acetylation (English)

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22 September 2017

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Gil Blander

1

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22 September 2017

Noa Zalle

2

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22 September 2017

Yaron Daniely

3

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22 September 2017

Jan Taplick

4

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22 September 2017

Matthew D Gray

5

1 reference

22 September 2017

Moshe Oren

6

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22 September 2017

language of work or name

English

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publication date

15 October 2002

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

277

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22 September 2017

50934-50940

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22 September 2017

52

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Unwinding the molecular basis of the Werner syndrome

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Positional cloning of the Werner's syndrome gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

DNA helicase deficiencies associated with cancer predisposition and premature ageing disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

The Bloom's syndrome gene product is homologous to RecQ helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

The Werner syndrome protein is a DNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Werner syndrome protein: biochemical properties and functional interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

The Werner syndrome protein: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Werner helicase is localized to transcriptionally active nucleoli of cycling cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Nucleolar localization of the Werner syndrome protein in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Functional and physical interaction between WRN helicase and human replication protein A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

p53-mediated apoptosis is attenuated in Werner syndrome cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Physical and functional interaction between p53 and the Werner's syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Werner protein recruits DNA polymerase delta to the nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

UV induces nucleolar translocation of ING1 through two distinct nucleolar targeting sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Regulation and localization of the Bloom syndrome protein in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Mechanisms of switching on p53: a role for covalent modification?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Post-translational modifications and activation of p53 by genotoxic stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Regulation of p53 localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Regulation of p53 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

p300/CBP/p53 interaction and regulation of the p53 response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Histone acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Acetylation regulates transcription factor activity at multiple levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Diverged nuclear localization of Werner helicase in human and mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Functional interaction between the Werner Syndrome protein and DNA polymerase delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Functional interaction between Ku and the werner syndrome protein in DNA end processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Covalent modification of the Werner's syndrome gene product with the ubiquitin-related protein, SUMO-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

The N-terminal internal region of BLM is required for the formation of dots/rod-like structures which are associated with SUMO-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Functional interaction of p53 and BLM DNA helicase in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

Regulation of p53 activity in nuclear bodies by a specific PML isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210479200

21 January 2018

Identifiers

DOI

10.1074/JBC.M210479200

1 reference

22 September 2017

1 reference