(Q40711462)

23 September 2017

Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling (English)

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23 September 2017

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GOA release 2020-03-11

author name string

Xinsheng Gao

1

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23 September 2017

Yong Zhang

2

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23 September 2017

Peter Arrazola

3

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23 September 2017

Okio Hino

4

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23 September 2017

Toshiyuki Kobayashi

5

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23 September 2017

Raymond S Yeung

6

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23 September 2017

Binggeng Ru

7

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23 September 2017

Duojia Pan

8

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23 September 2017

1 September 2002

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23 September 2017

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23 September 2017

4

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23 September 2017

699-704

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23 September 2017

9

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https://scigraph.springernature.com/pub.10.1038/ncb847

23 September 2017

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cites work

TOR signalling and control of cell growth

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Regulation of translation initiation by FRAP/mTOR

21 January 2018

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Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34

21 January 2018

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Identification and characterization of the tuberous sclerosis gene on chromosome 16

21 January 2018

1 reference

21 January 2018

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Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

21 January 2018

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Genetic control of cell size

21 January 2018

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The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation.

21 January 2018

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Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size.

21 January 2018

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TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth

21 January 2018

1 reference

The genetic basis of tuberous sclerosis.

21 January 2018

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Characterization of the cytosolic tuberin-hamartin complex. Tuberin is a cytosolic chaperone for hamartin

21 January 2018

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Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products

21 January 2018

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Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

21 January 2018

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Regulation of the p70 S6 kinase by phosphorylation in vivo. Analysis using site-specific anti-phosphopeptide antibodies.

21 January 2018

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dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1.

21 January 2018

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A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells

21 January 2018

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The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila

21 January 2018

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Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene

21 January 2018

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The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis

21 January 2018

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A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice

21 January 2018

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21 January 2018

The Hallmarks of Cancer

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gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle

21 January 2018

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Drosophila S6 kinase: a regulator of cell size.

21 January 2018

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Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin

21 January 2018

1 reference

Regulation of cellular growth by the Drosophila target of rapamycin dTOR

21 January 2018

1 reference

Antisocial, an intracellular adaptor protein, is required for myoblast fusion in Drosophila.

21 January 2018

1 reference

The SREBP pathway in Drosophila: regulation by palmitate, not sterols

21 January 2018

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Mammalian TOR: a homeostatic ATP sensor

21 January 2018

1 reference

The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/NCB847

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Dimensions Publication ID

23 September 2017

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